Protein: RSC8
Chromatin structure-remodeling complex protein RSC8 (Remodel the structure of chromatin complex subunit 8) (SWI3 homolog)

Gene: RSC8
Organism: Saccharomyces cerevisiae S288C
Interactions: 182
UniProt ID: P43609

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0006337 - nucleosome disassembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797953

SFH1
Chromatin structure-remodeling complex subunit SFH1

8

9

Small-scale

0.967

High

797910

RSC8
Chromatin structure-remodeling complex protein RSC8

3

15

Small-scale

0.845

High

797934

GCN5
Histone acetyltransferase GCN5

2

20

High-throughput

0.776

High

696223

STH1
Nuclear protein STH1/NPS1

13

20

Small-scale

0.761

High

797956

RSC2
Chromatin structure-remodeling complex subunit RSC2

14

20

Small-scale

0.759

High

635516

RSC6
Chromatin structure-remodeling complex protein RSC6

10

18

Small-scale

0.758

High

698666

RSC7
Chromatin structure-remodeling complex subunit RSC7

7

1

Small-scale

0.749

High

797975

ARP7
Actin-related protein 7

7

16

Small-scale

0.746

High

797930

RSC4
Chromatin structure-remodeling complex subunit RSC4

7

20

Small-scale

0.745

High

716278

SPT10
Protein SPT10

2

2

High-throughput

0.737

High

797932

HOS3
Histone deacetylase HOS3

2

5

High-throughput

0.737

High

797957

RSC3
Chromatin structure-remodeling complex protein RSC3

6

1

Small-scale

0.736

High

797922

RT102
Regulator of Ty1 transposition protein 102

6

1

High-throughput

0.735

High

797933

RSC9
Chromatin structure-remodeling complex subunit RSC9

9

0

Small-scale

0.722

High

797948

ARP9
Actin-like protein ARP9

5

18

High-throughput

0.718

High

797962

RSC58
Chromatin structure-remodeling complex protein RSC58

8

0

Small-scale

0.716

High

797981

HTL1
High temperature lethal protein 1

8

0

Small-scale

0.716

High

746447

LDB7
Chromatin structure-remodeling complex protein RSC14

2

0

Small-scale

0.716

High

797921

RSC1
Chromatin structure-remodeling complex subunit RSC1

5

20

Small-scale

0.712

High

356550

H4
Histone H4

5

4

Small-scale

0.709

High

797926

H3
Histone H3

5

13

Small-scale

0.706

High

754243

RSC30
Chromatin structure-remodeling complex protein RSC30

4

1

Small-scale

0.686

High

491609

HSP71
Heat shock protein SSA1

4

5

High-throughput

0.672

High

609105

SIN3
Transcriptional regulatory protein SIN3

3

4

High-throughput

0.657

High

375614

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

4

High-throughput

0.621

High

744879

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

20

High-throughput

0.621

High

770089

RT106
Histone chaperone RTT106

2

1

Small-scale

0.619

High

697407

CHD1
Chromo domain-containing protein 1

1

15

High-throughput

0.618

High

797950

IMB1
Importin subunit beta-1

2

3

High-throughput

0.612

High

606686

RPC2
DNA-directed RNA polymerase III subunit RPC2

2

3

High-throughput

0.611

High

797972

SCC1
Sister chromatid cohesion protein 1

2

2

Small-scale

0.611

High

511762

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.601

High

797947

TAF9
Transcription initiation factor TFIID subunit 9

2

8

High-throughput

0.601

High

692823

SPT16
FACT complex subunit SPT16

2

1

High-throughput

0.594

High

797936

STE20
Serine/threonine-protein kinase STE20

2

4

Small-scale

0.594

High

514260

NHP6B
Non-histone chromosomal protein 6B

2

14

High-throughput

0.588

High

639276

MSH2
DNA mismatch repair protein MSH2

2

1

High-throughput

0.588

High

797916

RFX1
RFX-like DNA-binding protein RFX1

2

3

High-throughput

0.588

High

797935

NHP10
Non-histone protein 10

2

13

High-throughput

0.588

High

797939

MSH6
DNA mismatch repair protein MSH6

2

1

High-throughput

0.588

High

772288

ATAD2
ATPase histone chaperone YTA7

2

2

Small-scale

0.584

High

693551

MED17
Mediator of RNA polymerase II transcription subunit 17

2

1

Small-scale

0.576

High

516305

RAP1
DNA-binding protein RAP1

1

1

High-throughput

0.575

High

603000

BAS1
Myb-like DNA-binding protein BAS1

1

10

High-throughput

0.575

High

355528

H2B1
Histone H2B.1

2

16

High-throughput

0.571

High

710443

SAS3
Histone acetyltransferase SAS3

2

1

High-throughput

0.571

High

797945

POB3
FACT complex subunit POB3

2

2

High-throughput

0.571

High

797949

SWR1
Helicase SWR1

2

20

High-throughput

0.571

High

797979

H2AZ
Histone H2A.Z

2

11

High-throughput

0.571

High

680809

HS104
Heat shock protein 104

2

0

High-throughput

0.569

High

515065

MCM1
Pheromone receptor transcription factor

2

1

High-throughput

0.552

High

633869

SGF29
SAGA-associated factor 29

1

6

High-throughput

0.536

High

744638

TAF5
Transcription initiation factor TFIID subunit 5

1

17

High-throughput

0.536

High

797920

SGF73
SAGA-associated factor 73

1

5

High-throughput

0.536

High

797931

ABF2
ARS-binding factor 2, mitochondrial

1

17

High-throughput

0.536

High

797940

HMO1
High mobility group protein 1

1

15

High-throughput

0.536

High

797973

SIZ2
E3 SUMO-protein ligase SIZ2

1

2

High-throughput

0.536

High

667863

MCM5
Minichromosome maintenance protein 5

2

0

High-throughput

0.528

High

701177

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.513

High

797745

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.513

High

603321

SNF2
Transcription regulatory protein SNF2

1

20

Small-scale

0.508

High

797914

CLA4
Serine/threonine-protein kinase CLA4

1

2

Small-scale

0.501

High

694948

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.500

High

797178

EPL1
Enhancer of polycomb-like protein 1

1

0

High-throughput

0.493

High

399521

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.489

High

710388

EDE1
EH domain-containing and endocytosis protein 1

1

1

High-throughput

0.481

High

355924

H2B2
Histone H2B.2

1

16

High-throughput

0.479

High

392479

H2A2
Histone H2A.2

1

11

High-throughput

0.479

High

407135

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

412792

KAPA
cAMP-dependent protein kinase type 1

1

2

Small-scale

0.479

High

420140

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.479

High

423686

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.479

High

527019

TBP
TATA-box-binding protein

1

3

High-throughput

0.479

High

558120

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

751321

RFC1
Replication factor C subunit 1

1

2

High-throughput

0.479

High

607297

RFA1
Replication factor A protein 1

1

2

Small-scale

0.479

High

662567

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

687712

BTAF1
TATA-binding protein-associated factor MOT1

1

20

Small-scale

0.479

High

688300

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

698853

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.479

High

715701

TAF14
Transcription initiation factor TFIID subunit 14

1

5

Small-scale

0.479

High

716452

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

728270

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.479

High

728711

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.479

High

730839

CENPA
Histone H3-like centromeric protein CSE4

1

13

High-throughput

0.479

High

742858

GBLP
Small ribosomal subunit protein RACK1

1

13

High-throughput

0.479

High

775755

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

797438

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

797923

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

797924

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

797927

CTF4
DNA polymerase alpha-binding protein

1

8

High-throughput

0.479

High

797941

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

797942

SIZ1
E3 SUMO-protein ligase SIZ1

1

2

High-throughput

0.479

High

797954

YL455
PWWP domain-containing protein YLR455W

1

1

High-throughput

0.479

High

797960

BDF2
Bromodomain-containing factor 2

1

18

High-throughput

0.479

High

797964

MED7
Mediator of RNA polymerase II transcription subunit 7

1

3

Small-scale

0.479

High

797965

YNG1
Protein YNG1

1

4

Small-scale

0.479

High

797967

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.479

High

797971

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

797974

NTO1
NuA3 HAT complex component NTO1

1

1

High-throughput

0.479

High

797976

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.479

High

797978

CMR1
DNA damage-binding protein CMR1

1

10

High-throughput

0.479

High

797980

SMC6
Structural maintenance of chromosomes protein 6

1

4

High-throughput

0.479

High

644763

RFA2
Replication factor A protein 2

1

1

High-throughput

0.470

High

601762

RCC1
Guanine nucleotide exchange factor SRM1

1

0

Small-scale

0.458

High

628201

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

774922

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.458

High

797943

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.458

High

797944

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

797951

NEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.458

High

797952

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

797955

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

797966

SGO1
Shugoshin

1

0

High-throughput

0.458

High

797970

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.458

High

366489

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

419353

HAP2
Transcriptional activator HAP2

1

4

High-throughput

0.445

High

457037

SWI6
Regulatory protein SWI6

1

2

High-throughput

0.445

High

514191

NHP6A
Non-histone chromosomal protein 6A

1

13

High-throughput

0.445

High

605235

AFT1
Iron-regulated transcriptional activator AFT1

1

2

High-throughput

0.445

High

628873

SWI4
Regulatory protein SWI4

1

2

High-throughput

0.445

High

689899

ASF1
Histone chaperone ASF1

1

3

High-throughput

0.445

High

690842

HIR1
Protein HIR1

1

13

High-throughput

0.445

High

691908

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

High-throughput

0.445

High

705893

IXR1
Intrastrand cross-link recognition protein

1

13

High-throughput

0.445

High

706972

MSN2
Zinc finger protein MSN2

1

7

High-throughput

0.445

High

707026

MSN4
Zinc finger protein MSN4

1

6

High-throughput

0.445

High

715346

SPT7
Transcriptional activator SPT7

1

20

High-throughput

0.445

High

733260

SET3
SET domain-containing protein 3

1

8

High-throughput

0.445

High

755777

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

5

High-throughput

0.445

High

768749

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

797911

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.445

High

797912

TEA1
TY1 enhancer activator

1

4

High-throughput

0.445

High

797918

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

9

High-throughput

0.445

High

797937

TAF12
Transcription initiation factor TFIID subunit 12

1

5

High-throughput

0.445

High

797938

GIS1
Transcriptional activator/repressor GIS1

1

4

High-throughput

0.445

High

797946

RCO1
Transcriptional regulatory protein RCO1

1

14

High-throughput

0.445

High

797969

HFI1
Transcriptional coactivator HFI1/ADA1

1

2

High-throughput

0.445

High

797977

RLF2
Chromatin assembly factor 1 subunit p90

1

3

High-throughput

0.445

High

141396

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

358127

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

383213

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

405688

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

407982

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

413579

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

426013

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

471122

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472256

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

480169

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

480739

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

482317

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

543955

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.437

High

631947

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.437

High

645514

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

700482

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

700959

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

706340

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

729974

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

752520

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

797915

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

797919

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

6

High-throughput

0.437

High

797928

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

797968

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

535768

ABF1
ARS-binding factor 1

1

0

High-throughput

0.426

High

709299

MKS1
Negative regulator of RAS-cAMP pathway

1

0

High-throughput

0.426

High

797925

MOT3
Transcriptional activator/repressor MOT3

1

0

High-throughput

0.426

High

368175

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.407

High

424578

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.407

High

556129

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

763653

GEM1
Mitochondrial Rho GTPase 1

1

1

High-throughput

0.407

High

785076

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

797958

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.407

High

797959

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.407

High

797929

MRS2
Magnesium transporter MRS2, mitochondrial

1

0

High-throughput

0.251

Low

613128

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.249

Low

797961

HBT1
Protein HBT1

1

0

High-throughput

0.249

Low

797963

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low

535986

CHS2
Chitin synthase 2

1

0

High-throughput

0.232

Low

761476

MNN9
Mannan polymerase complexes subunit MNN9

1

0

High-throughput

0.232

Low

774774

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low

797913

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.232

Low

797917

CCH1
Calcium-channel protein CCH1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024