Protein: FKBP4
FK506-binding protein 4 (EC 5.2.1.8) (Histone proline isomerase) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)

Gene: FKBP4, FPR4
Organism: Saccharomyces cerevisiae S288C
Interactions: 169
UniProt ID: Q06205

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005527 - macrolide binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

696408

PP12
Serine/threonine-protein phosphatase PP1-2

3

3

High-throughput

0.855

High

986469

FKBP4
FK506-binding protein 4

3

11

Small-scale

0.821

High

757349

FKBP3
Peptidyl-prolyl cis-trans isomerase

3

11

High-throughput

0.812

High

902075

H3
Histone H3

6

7

Small-scale

0.734

High

550126

CSK21
Casein kinase II subunit alpha

2

11

High-throughput

0.712

High

584801

CSK22
Casein kinase II subunit alpha'

2

12

High-throughput

0.712

High

733939

RPF2
Ribosome biogenesis protein RPF2

4

4

High-throughput

0.697

High

356734

H4
Histone H4

4

5

Small-scale

0.692

High

797396

LOC1
60S ribosomal subunit assembly/export protein LOC1

4

1

High-throughput

0.690

High

986489

NOP53
Ribosome biogenesis protein NOP53

4

1

Small-scale

0.680

High

978433

RRP17
Ribosomal RNA-processing protein 17

4

1

High-throughput

0.674

High

764246

NOC2
Nucleolar complex protein 2

3

3

High-throughput

0.669

High

980157

ERB1
Ribosome biogenesis protein ERB1

3

7

High-throughput

0.667

High

778861

NOP2
25S rRNA

3

5

High-throughput

0.662

High

638861

SPB4
ATP-dependent rRNA helicase SPB4

3

8

High-throughput

0.656

High

766704

NUG1
Nuclear GTP-binding protein NUG1

3

2

High-throughput

0.656

High

973460

NOG1
Nucleolar GTP-binding protein 1

3

5

Small-scale

0.656

High

634448

SPB1
27S pre-rRNA

3

2

High-throughput

0.646

High

731868

EBP2
rRNA-processing protein EBP2

3

2

High-throughput

0.646

High

859509

NSA1
Ribosome biogenesis protein NSA1

3

1

Small-scale

0.640

High

597902

PWP1
Periodic tryptophan protein 1

2

3

High-throughput

0.621

High

986484

HRK1
Serine/threonine-protein kinase HRK1

1

6

High-throughput

0.618

High

339850

CDK1
Cyclin-dependent kinase 1

1

6

High-throughput

0.618

High

986494

SMT3
Ubiquitin-like protein SMT3

1

5

High-throughput

0.618

High

979449

PUF6
Pumilio homology domain family member 6

2

3

High-throughput

0.611

High

986476

NOC3
Nucleolar complex-associated protein 3

2

4

High-throughput

0.611

High

986479

NOP12
Nucleolar protein 12

2

5

High-throughput

0.594

High

775263

ULP2
Ubiquitin-like-specific protease 2

2

3

High-throughput

0.586

High

594071

MAK11
Protein MAK11

2

6

Small-scale

0.584

High

754914

SSF1
Ribosome biogenesis protein SSF1

2

1

Small-scale

0.584

High

776517

RLP7
Ribosome biogenesis protein RLP7

2

3

High-throughput

0.584

High

860888

PESC
Pescadillo homolog

2

3

High-throughput

0.584

High

866266

NOP15
Ribosome biogenesis protein 15

2

5

High-throughput

0.584

High

976861

HAS1
ATP-dependent RNA helicase HAS1

2

9

High-throughput

0.584

High

986488

YTM1
Ribosome biogenesis protein YTM1

2

9

High-throughput

0.584

High

865619

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

4

High-throughput

0.576

High

643208

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

3

High-throughput

0.575

High

696534

TOR2
Serine/threonine-protein kinase TOR2

1

8

High-throughput

0.575

High

392576

H2A2
Histone H2A.2

2

2

High-throughput

0.571

High

743005

GBLP
Small ribosomal subunit protein RACK1

2

8

High-throughput

0.571

High

755332

RPF1
Ribosome production factor 1

2

2

High-throughput

0.571

High

772340

ATAD2
ATPase histone chaperone YTA7

2

6

High-throughput

0.571

High

986497

H2AZ
Histone H2A.Z

2

7

High-throughput

0.571

High

544446

HSC82
ATP-dependent molecular chaperone HSC82

1

13

High-throughput

0.553

High

512800

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.552

High

798387

CSK2B
Casein kinase II subunit beta

2

2

High-throughput

0.552

High

676385

XPO1
Exportin-1

1

2

High-throughput

0.536

High

859434

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

2

High-throughput

0.536

High

965041

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

5

High-throughput

0.536

High

975969

GCN5
Histone acetyltransferase GCN5

1

4

High-throughput

0.536

High

986475

RIX7
Ribosome biogenesis ATPase RIX7

1

4

High-throughput

0.536

High

655900

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.518

High

641069

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

767112

YEN1
Holliday junction resolvase YEN1

1

0

High-throughput

0.513

High

977767

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.513

High

404708

RL7A
Large ribosomal subunit protein uL30A

1

3

High-throughput

0.489

High

864610

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.489

High

696671

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.486

High

972016

ULP1
Ubiquitin-like-specific protease 1

1

3

High-throughput

0.481

High

141532

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

375508

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

407329

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

480325

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

501250

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

604621

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

4

High-throughput

0.479

High

634777

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

645660

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

663366

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

663917

TF3B
Transcription factor IIIB 70 kDa subunit

1

5

High-throughput

0.479

High

681006

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

688432

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

699730

DRS1
ATP-dependent RNA helicase DRS1

1

6

High-throughput

0.479

High

703117

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.479

High

715487

RRP1
Ribosomal RNA-processing protein 1

1

2

High-throughput

0.479

High

732246

RRP14
Ribosomal RNA-processing protein 14

1

1

High-throughput

0.479

High

742068

NOP4
Nucleolar protein 4

1

1

High-throughput

0.479

High

746267

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

748708

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

754193

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.479

High

766597

NOP16
Nucleolar protein 16

1

1

High-throughput

0.479

High

768049

NSA2
Ribosome biogenesis protein NSA2

1

2

High-throughput

0.479

High

792586

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.479

High

812127

MOG1
Nuclear import protein MOG1

1

3

High-throughput

0.479

High

841439

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.479

High

865759

NOP13
Nucleolar protein 13

1

1

High-throughput

0.479

High

866487

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

872809

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.479

High

975835

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

979026

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

979106

RRB1
Ribosome assembly protein RRB1

1

3

High-throughput

0.479

High

984213

HRQ1
ATP-dependent helicase HRQ1

1

2

Small-scale

0.479

High

986408

YL455
PWWP domain-containing protein YLR455W

1

2

High-throughput

0.479

High

986470

JIP5
WD repeat-containing protein JIP5

1

4

High-throughput

0.479

High

986471

DBP9
ATP-dependent RNA helicase DBP9

1

4

High-throughput

0.479

High

986472

RRP15
Ribosomal RNA-processing protein 15

1

1

High-throughput

0.479

High

986473

NOC4
Nucleolar complex protein 4

1

6

High-throughput

0.479

High

986477

RLP24
Ribosome biogenesis protein RLP24

1

1

High-throughput

0.479

High

986480

BRX1
Ribosome biogenesis protein BRX1

1

13

High-throughput

0.479

High

986483

SGO1
Shugoshin

1

1

High-throughput

0.479

High

986486

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.479

High

986487

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

986490

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

986491

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

986492

RL7B
Large ribosomal subunit protein uL30B

1

3

High-throughput

0.479

High

986495

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.479

High

986496

IF6
Eukaryotic translation initiation factor 6

1

3

High-throughput

0.479

High

408133

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413716

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

632099

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

756870

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

978293

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

978693

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.458

High

691428

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

1

High-throughput

0.457

High

986482

RTC1
Restriction of telomere capping protein 1

1

5

High-throughput

0.457

High

355650

H2B1
Histone H2B.1

1

4

High-throughput

0.445

High

356018

H2B2
Histone H2B.2

1

4

High-throughput

0.445

High

454468

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.445

High

492494

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

495006

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.445

High

733310

SET3
SET domain-containing protein 3

1

2

High-throughput

0.445

High

756184

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

1

High-throughput

0.445

High

757966

CSK2C
Casein kinase II subunit beta'

1

2

High-throughput

0.445

High

767423

UTP7
U3 small nucleolar RNA-associated protein 7

1

5

High-throughput

0.445

High

769523

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

805021

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

1

Small-scale

0.445

High

809637

YPP1
Cargo-transport protein YPP1

1

1

High-throughput

0.445

High

810365

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

High-throughput

0.445

High

866861

RCM1
25S rRNA

1

5

High-throughput

0.445

High

960010

SEN1
Helicase SEN1

1

3

Small-scale

0.445

High

977697

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.445

High

981816

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.445

High

986478

BUD20
Bud site selection protein 20

1

1

High-throughput

0.445

High

986493

RLM1
Transcription factor RLM1

1

1

High-throughput

0.445

High

859984

CGR1
rRNA-processing protein CGR1

1

0

High-throughput

0.438

High

862739

H1
Histone H1

1

0

High-throughput

0.438

High

405839

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

426159

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

471263

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

480890

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

482467

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

645138

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

706496

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

730123

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

752676

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

762025

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.437

High

762574

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

820180

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

959876

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

967769

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

986474

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

986485

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

986498

RS22B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.437

High

774751

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.426

High

982943

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.426

High

361037

TBB
Tubulin beta chain

1

2

High-throughput

0.407

High

368422

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.407

High

399640

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.407

High

424719

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.407

High

741352

STT4
Phosphatidylinositol 4-kinase STT4

1

4

High-throughput

0.407

High

805169

STU2
Protein STU2

1

1

High-throughput

0.407

High

710692

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

535122

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.279

Low

358265

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

478992

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

745897

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

860379

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

540163

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

986481

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024