Protein: PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16)

Gene: PP2AA, Ppp2ca
Organism: Mus musculus
Interactions: 61
UniProt ID: P63330

Gene Ontology (top 5):
GO:0000159 - protein phosphatase type 2A complex
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0000922 - spindle pole
GO:0004722 - protein serine/threonine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

994005

IGBP1
Immunoglobulin-binding protein 1

2

20

Small-scale

0.800

High

994011

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

20

Small-scale

0.757

High

533373

RRAS
Ras-related protein R-Ras

1

3

Small-scale

0.665

High

205256

AXIN1
Axin-1

2

5

Small-scale

0.631

High

946227

PTPA
Serine/threonine-protein phosphatase 2A activator

1

12

Small-scale

0.618

High

978444

RHOB
Rho-related GTP-binding protein RhoB

1

6

Small-scale

0.618

High

993089

ACTG
Actin, cytoplasmic 2

1

8

Small-scale

0.618

High

994009

INT6
Integrator complex subunit 6

1

5

Small-scale

0.618

High

994010

NEB2
Neurabin-2

1

20

High-throughput

0.618

High

994013

ERBIN
Erbin

1

12

High-throughput

0.618

High

994023

Q91V89
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit

1

20

High-throughput

0.618

High

994003

PPP5
Serine/threonine-protein phosphatase 5

1

14

Small-scale

0.590

High

530779

TAU
Microtubule-associated protein tau

2

12

Small-scale

0.584

High

312607

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

9

Small-scale

0.561

High

662961

MDM2
E3 ubiquitin-protein ligase Mdm2

1

3

Small-scale

0.561

High

921231

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

Small-scale

0.561

High

108317

G3X9E8
Protein phosphatase 2, regulatory subunit B'', alpha

1

6

Small-scale

0.553

High

771455

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

6

High-throughput

0.536

High

994001

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

5

High-throughput

0.536

High

994017

FTM
Protein fantom

1

12

High-throughput

0.536

High

847011

H11
Histone H1.1

1

2

Small-scale

0.501

High

994016

KCD20
BTB/POZ domain-containing protein KCTD20

1

7

Small-scale

0.501

High

994024

ARRB2
Beta-arrestin-2

1

0

Small-scale

0.480

High

205288

NR1I3
Nuclear receptor subfamily 1 group I member 3

1

8

Small-scale

0.479

High

522160

BCL2
Apoptosis regulator Bcl-2

1

11

Small-scale

0.479

High

703988

DUS1
Dual specificity protein phosphatase 1

1

4

Small-scale

0.479

High

713194

NOS2
Nitric oxide synthase, inducible

1

2

Small-scale

0.479

High

728515

AKT1
RAC-alpha serine/threonine-protein kinase

1

15

Small-scale

0.479

High

993993

NOS3
Nitric oxide synthase 3

1

2

High-throughput

0.479

High

993995

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

6

High-throughput

0.479

High

993997

TERA
Transitional endoplasmic reticulum ATPase

1

6

Small-scale

0.479

High

993998

APLP2
Amyloid beta precursor like protein 2

1

5

Small-scale

0.479

High

994000

Q3UJF1
Histone deacetylase

1

16

High-throughput

0.479

High

994004

KSR1
Kinase suppressor of Ras 1

1

11

Small-scale

0.479

High

994006

ACVL1
Activin receptor type-1-like

1

6

High-throughput

0.479

High

994008

HDAC4
Histone deacetylase 4

1

18

Small-scale

0.479

High

994012

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

8

Small-scale

0.479

High

994014

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

994019

UNC5B
Netrin receptor UNC5B

1

2

Small-scale

0.479

High

994021

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

9

Small-scale

0.479

High

994025

RING2
E3 ubiquitin-protein ligase RING2

1

6

Small-scale

0.479

High

994026

INT11
Integrator complex subunit 11

1

4

Small-scale

0.479

High

994029

WDR12
Ribosome biogenesis protein WDR12

1

7

Small-scale

0.479

High

994032

ERN2
Serine/threonine-protein kinase/endoribonuclease IRE2

1

8

Small-scale

0.479

High

687630

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.458

High

993994

ADCY8
Adenylate cyclase type 8

1

0

Small-scale

0.458

High

993996

NDKB
Nucleoside diphosphate kinase B

1

0

Small-scale

0.458

High

994002

EPHA5
Ephrin type-A receptor 5

1

0

Small-scale

0.458

High

994018

PDXK
Pyridoxal kinase

1

0

Small-scale

0.458

High

994020

BBS7
BBSome complex member BBS7

1

0

Small-scale

0.458

High

994031

HEBP2
Heme-binding protein 2

1

0

Small-scale

0.458

High

994033

HDAC5
Histone deacetylase 5

1

16

High-throughput

0.445

High

108610

G3X9H5
Huntingtin

1

2

High-throughput

0.437

High

810545

DYN2
Dynamin-2

1

1

Small-scale

0.437

High

993999

F184B
Protein FAM184B

1

11

Small-scale

0.437

High

994022

CBPZ
Carboxypeptidase Z

1

7

High-throughput

0.437

High

994027

RT09
Small ribosomal subunit protein uS9m

1

1

Small-scale

0.437

High

994007

EGLN
Endoglin

1

0

High-throughput

0.249

Low

994015

IMPG2
Interphotoreceptor matrix proteoglycan 2

1

0

Small-scale

0.249

Low

994028

MZB1
Marginal zone B- and B1-cell-specific protein

1

0

Small-scale

0.249

Low

994030

DERM
Dermatopontin

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025