Protein: RRP6
Exosome complex exonuclease rrp6 (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)

Gene: RRP6
Organism: Schizosaccharomyces pombe 972h-
Interactions: 54
UniProt ID: Q10146

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

151585

YE02
Uncharacterized helicase C17H9.02

2

5

High-throughput

0.754

High

789315

DIS3
Exosome complex exonuclease dis3

3

5

Small-scale

0.640

High

153555

MTR4
ATP-dependent RNA helicase mtr4

1

5

High-throughput

0.618

High

207023

DHX15
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43

1

2

High-throughput

0.618

High

267723

YQC7
Exosome complex protein C1739.07

1

1

High-throughput

0.618

High

1082702

RRP6
Exosome complex exonuclease rrp6

1

5

High-throughput

0.618

High

1082704

DBP3
ATP-dependent RNA helicase dbp3

1

1

High-throughput

0.618

High

1082706

YBH9
Uncharacterized protein C3B8.09

1

1

High-throughput

0.618

High

1082717

RED1
NURS complex subunit red1

2

1

Small-scale

0.601

High

206564

FFT3
ATP-dependent helicase fft3

1

0

High-throughput

0.586

High

1082705

RRP43
Exosome complex component rrp43

2

12

Small-scale

0.584

High

151693

EBP2
Probable rRNA-processing protein ebp2

1

1

High-throughput

0.479

High

151956

MPP10
U3 small nucleolar ribonucleoprotein protein mpp10

1

3

High-throughput

0.479

High

152400

SGD1
Suppressor of glycerol defect protein 1

1

2

High-throughput

0.479

High

268116

GRN1
GTPase grn1

1

2

High-throughput

0.479

High

314631

SIR2
NAD-dependent histone deacetylase sir2

1

4

High-throughput

0.479

High

314708

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

828292

XRN2
5'-3' exoribonuclease 2

1

2

Small-scale

0.479

High

836494

GAR2
Protein gar2

1

2

High-throughput

0.479

High

1017968

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.479

High

1067050

MLO3
mRNA export protein mlo3

1

4

High-throughput

0.479

High

1068419

RRP4
Exosome complex component rrp4

1

5

High-throughput

0.479

High

1082707

YL92
Uncharacterized protein C683.02c

1

4

High-throughput

0.479

High

1082708

UTP7
Probable U3 small nucleolar RNA-associated protein 7

1

6

High-throughput

0.479

High

1082709

TF3B
Transcription factor IIIB 60 kDa subunit

1

1

High-throughput

0.479

High

1082710

YNY5
LisH domain-containing protein C1711.05

1

1

High-throughput

0.479

High

1082711

YKU5
Uncharacterized WD repeat-containing protein C2E1P5.05

1

7

High-throughput

0.479

High

1082713

BFR2
Protein bfr2

1

1

High-throughput

0.479

High

1082716

CID14
Poly(A) RNA polymerase cid14

1

4

High-throughput

0.479

High

152716

MPP6
M-phase phosphoprotein 6 homolog

1

0

High-throughput

0.458

High

153733

YFPE
Uncharacterized protein C7D4.14c

1

0

High-throughput

0.458

High

153900

PAB2
Polyadenylate-binding protein 2

1

0

Small-scale

0.458

High

206089

SPB1
AdoMet-dependent rRNA methyltransferase spb1

1

0

High-throughput

0.458

High

238250

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

268215

YBJC
Zinc finger CCCH domain-containing protein C337.12

1

0

High-throughput

0.458

High

268294

ESF1
Pre-rRNA-processing protein esf1

1

0

High-throughput

0.458

High

268741

MMI1
RNA binding exosome specificity factor Mmi1

1

0

High-throughput

0.458

High

313812

PIR2
NURS complex subunit pir2

1

0

High-throughput

0.458

High

314079

CWC26
Pre-mRNA-splicing factor cwf26

1

0

High-throughput

0.458

High

314538

JHD1
Putative JmjC domain-containing histone demethylation protein 1

1

0

High-throughput

0.458

High

314811

IPI1
Pre-rRNA-processing protein ipi1

1

0

High-throughput

0.458

High

1018134

RIX1
Pre-rRNA-processing protein rix1

1

0

High-throughput

0.458

High

1068559

FIP1X
Pre-mRNA polyadenylation factor fip1

1

0

Small-scale

0.458

High

1082703

YAW8
Uncharacterized protein C3F10.08c

1

0

High-throughput

0.458

High

1082712

PXR1
Protein pxr1

1

0

High-throughput

0.458

High

1082714

SIM3
NASP-related protein sim3

1

0

High-throughput

0.458

High

1082715

MRT4
Ribosome assembly factor mrt4

1

0

High-throughput

0.458

High

1082718

GRC3
Polynucleotide 5'-hydroxyl-kinase grc3

1

0

High-throughput

0.458

High

1082719

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.458

High

1082720

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

237661

RAD14
DNA repair protein rad14

1

1

High-throughput

0.437

High

267852

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.437

High

1068551

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High


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Last updated: 11Aug2025