Protein: OGA
Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylglucosaminidase) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (NCOAT)

Gene: OGA
Organism: Homo sapiens
Interactions: 72
UniProt ID: O60502

Gene Ontology (top 5):
GO:0004415 - hyalurononglucosaminidase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006044 - N-acetylglucosamine metabolic process
GO:0006493 - protein O-linked glycosylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

235249

OGA
Protein O-GlcNAcase

2

1

Small-scale

0.768

High

174474

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

3

0

Small-scale

0.647

High

235304

STN1
CST complex subunit STN1

3

0

High-throughput

0.638

High

235267

FMO5
Flavin-containing monooxygenase 5

2

0

High-throughput

0.602

High

235271

RIDA
2-iminobutanoate/2-iminopropanoate deaminase

2

0

High-throughput

0.602

High

235280

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

2

0

High-throughput

0.602

High

235255

P53
Cellular tumor antigen p53

2

0

Small-scale

0.569

High

235260

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.547

High

235279

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.518

High

235303

RNF32
RING finger protein 32

1

0

High-throughput

0.518

High

235256

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.513

High

235268

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.513

High

235305

CBX8
Chromobox protein homolog 8

1

0

High-throughput

0.513

High

235311

S30BP
SAP30-binding protein

1

0

High-throughput

0.513

High

146571

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.493

High

235306

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.493

High

235270

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

235274

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

235312

XPO7
Exportin-7

1

1

High-throughput

0.479

High

235269

PSN2
Presenilin-2

1

0

High-throughput

0.460

High

225996

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

235251

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

235253

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

235262

EZRI
Ezrin

1

0

High-throughput

0.458

High

235263

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

235264

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

235266

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

235273

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

235275

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

235276

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

235277

IRF5
Interferon regulatory factor 5

1

0

Small-scale

0.458

High

235278

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

235281

FBX43
F-box only protein 43

1

0

Small-scale

0.458

High

235286

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

235289

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.458

High

235290

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

235291

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

235293

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

235294

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

235300

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.458

High

235308

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

0

Small-scale

0.458

High

235309

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

235310

TES
Testin

1

0

High-throughput

0.458

High

235315

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

235259

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

235272

HAP1
Huntingtin-associated protein 1

1

0

High-throughput

0.438

High

235297

SPAG5
Sperm-associated antigen 5

1

0

High-throughput

0.438

High

235288

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

217848

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.426

High

235283

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

235299

CK5P2
CDK5 regulatory subunit-associated protein 2

1

0

High-throughput

0.426

High

235257

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

3

0

High-throughput

0.347

High

235284

PPR18
Phostensin

3

0

High-throughput

0.347

High

235282

LACB2
Endoribonuclease LACTB2

3

0

High-throughput

0.342

High

235314

EMC9
ER membrane protein complex subunit 9

2

0

High-throughput

0.328

High

235252

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.282

High

235313

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.282

High

235250

LGI1
Leucine-rich glioma-inactivated protein 1

1

0

High-throughput

0.279

Low

235261

ACYP2
Acylphosphatase-2

1

0

High-throughput

0.279

Low

235285

S2547
Solute carrier family 25 member 47

1

0

High-throughput

0.279

Low

235298

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

235254

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

235258

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

235265

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

235287

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

235292

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.249

Low

235295

Q96BE0
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

235296

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low

235301

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.249

Low

235302

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.249

Low

235307

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024