HitPredict

Interactor 1: PUB3 (O14326)
E3 ubiquitin-protein ligase pub3 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase pub3)
Gene: PUB3

Interactor 2: RL402 (P0CH07)
Ubiquitin-ribosomal protein eL40B fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40B (60S ribosomal protein L40) (CEP52)]
Gene: uep1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 786 Sp			1 128
+	Sp
		153853 PUB3_SCHPO (1-786): 0: 838: 100.00		RS27A_SCHPO (1-71): 6.08e-32: 112: 100.00
+	Sp
		153854 PUB3_SCHPO (1-786): 0: 838: 100.00		RS27B_SCHPO (1-71): 4.11e-32: 112: 100.00
+	Sc
		509564 RSP5_YEAST (5-786): 0: 757: 54.73		UBI4P_YEAST (1-76): 1.64e-41: 142: 100.00
+	Sc
		436424 RSP5_YEAST (5-786): 0: 757: 54.73		RS31_YEAST (1-76): 2.5e-42: 138: 100.00
+	Hs
		987478 SMUF2_HUMAN (3-786): 0: 717: 35.27		RL40_HUMAN (1-128): 4e-55: 170: 90.63
+	Hs
		131925 WWP2_HUMAN (29-786): 0: 738: 36.77		RS27A_HUMAN (1-88): 1.84e-37: 126: 84.09
+	Hs
		987205 WWP1_HUMAN (4-786): 0: 728: 32.62		RS27A_HUMAN (1-88): 1.84e-37: 126: 84.09
+	Hs
		131689 WWP2_HUMAN (29-786): 0: 738: 36.77		UBB_HUMAN (1-76): 2.1e-32: 115: 96.05
+	Hs
		507377 SMUF2_HUMAN (3-786): 0: 717: 35.27		UBB_HUMAN (1-76): 2.1e-32: 115: 96.05
+	Hs
		507318 ITCH_HUMAN (144-786): 0: 706: 42.38		UBB_HUMAN (1-76): 2.1e-32: 115: 96.05
+	Hs
		987397 HUWE1_HUMAN (178-785): 1.08e-163: 528: 32.03		RL40_HUMAN (1-128): 4e-55: 170: 90.63
+	Dm
		94226 D5SHR3_DROME (371-786): 4.35e-174: 509: 45.39		RL40_DROME (1-128): 2.39e-55: 170: 92.19
+	Sc
		509922 TOM1_YEAST (380-785): 3.17e-154: 500: 41.93		RL40A_YEAST (1-128): 8.59e-54: 166: 96.88
+	Mm
		987293 HUWE1_MOUSE (337-785): 3.91e-163: 526: 40.18		RS27A_MOUSE (1-88): 2.06e-37: 125: 84.09
+	Sp
		151804 PTR1_SCHPO (407-784): 2.47e-155: 503: 42.19		UBI4P_SCHPO (1-77): 8.91e-42: 143: 98.70
+	At
		1167700 UPL1_ARATH (279-784): 1.54e-162: 524: 35.37		UBQ3_ARATH (1-77): 4.94e-34: 121: 96.10
+	Hs
		507253 HUWE1_HUMAN (178-785): 1.08e-163: 528: 32.03		UBB_HUMAN (1-76): 2.1e-32: 115: 96.05
+	Sc
		509696 TOM1_YEAST (380-785): 3.17e-154: 500: 41.93		UBI4P_YEAST (1-76): 1.64e-41: 142: 100.00
+	At
		1167704 UPL2_ARATH (382-784): 4.3e-161: 520: 42.38		UBQ3_ARATH (1-77): 4.94e-34: 121: 96.10
+	Sc
		436502 TOM1_YEAST (380-785): 3.17e-154: 500: 41.93		RS31_YEAST (1-76): 2.5e-42: 138: 100.00