Protein: XAF1
XIAP-associated factor 1 (BIRC4-binding protein)

Gene: XAF1
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q6GPH4

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1151556

RN114
E3 ubiquitin-protein ligase RNF114

6

6

Small-scale

0.739

High

957722

XIAP
E3 ubiquitin-protein ligase XIAP

5

5

Small-scale

0.717

High

1151547

RN166
E3 ubiquitin-protein ligase RNF166

4

7

Small-scale

0.702

High

681899

AKT1
RAC-alpha serine/threonine-protein kinase

3

1

High-throughput

0.665

High

1151548

BIRC7
Baculoviral IAP repeat-containing protein 7

3

4

Small-scale

0.660

High

584988

RO52
E3 ubiquitin-protein ligase TRIM21

2

3

High-throughput

0.606

High

1151542

LRSM1
E3 ubiquitin-protein ligase LRSAM1

2

1

High-throughput

0.606

High

1151543

TRI50
E3 ubiquitin-protein ligase TRIM50

2

2

High-throughput

0.606

High

1151544

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

3

High-throughput

0.606

High

1151552

TRI54
Tripartite motif-containing protein 54

2

4

High-throughput

0.606

High

501059

IRF1
Interferon regulatory factor 1

2

0

Small-scale

0.598

High

777881

RFC5
Replication factor C subunit 5

2

0

High-throughput

0.580

High

836490

SPS1
Selenide, water dikinase 1

2

0

High-throughput

0.580

High

875028

TERA
Transitional endoplasmic reticulum ATPase

2

0

High-throughput

0.580

High

1062076

UBX2B
UBX domain-containing protein 2B

2

0

High-throughput

0.580

High

1151555

GLSL
Glutaminase liver isoform, mitochondrial

2

0

High-throughput

0.580

High

502212

BIP
Endoplasmic reticulum chaperone BiP

1

1

Small-scale

0.561

High

749590

BRCA1
Breast cancer type 1 susceptibility protein

1

2

Small-scale

0.561

High

199120

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

5

Small-scale

0.552

High

369808

ESR1
Estrogen receptor

1

0

Small-scale

0.537

High

386920

P53
Cellular tumor antigen p53

1

0

Small-scale

0.537

High

1151546

CBP
CREB-binding protein

1

0

Small-scale

0.537

High

682188

AKT2
RAC-beta serine/threonine-protein kinase

1

1

High-throughput

0.536

High

1151550

TRI11
E3 ubiquitin-protein ligase TRIM11

1

2

High-throughput

0.536

High

1151551

TRI47
E3 ubiquitin-protein ligase TRIM47

1

3

High-throughput

0.536

High

1035824

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

Small-scale

0.515

High

1036285

BIRC2
Baculoviral IAP repeat-containing protein 2

1

4

Small-scale

0.515

High

1151541

TATD1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.513

High

1151549

HBAP1
HSPB1-associated protein 1

1

0

High-throughput

0.513

High

1151553

ASPC1
Tether containing UBX domain for GLUT4

1

0

High-throughput

0.513

High

394928

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

154202

CHK1
Serine/threonine-protein kinase Chk1

1

1

Small-scale

0.479

High

965384

TSPY1
Testis-specific Y-encoded protein 1

1

1

High-throughput

0.479

High

1020731

TRAF2
TNF receptor-associated factor 2

1

9

Small-scale

0.479

High

1023639

BIRC1
Baculoviral IAP repeat-containing protein 1

1

4

Small-scale

0.479

High

1038268

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

4

Small-scale

0.479

High

1151554

HIPK2
Homeodomain-interacting protein kinase 2

1

2

Small-scale

0.479

High

478702

TSPY3
Testis-specific Y-encoded protein 3

1

1

High-throughput

0.445

High

1110162

T10IP
Testis-specific protein 10-interacting protein

1

0

High-throughput

0.279

Low

1132847

DPS1
All trans-polyprenyl-diphosphate synthase PDSS1

1

0

High-throughput

0.279

Low

1151545

OR4X2
Olfactory receptor 4X2

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024