Protein: PKHA2
Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (Tandem PH domain-containing protein 2) (TAPP-2)

Gene: PKHA2, PLEKHA2
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q9HB19

Gene Ontology (top 5):
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0001968 - fibronectin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1033853

SNTA1
Alpha-1-syntrophin

2

18

Small-scale

0.789

High

1033921

SNTB2
Beta-2-syntrophin

2

18

Small-scale

0.789

High

734776

TRI23
E3 ubiquitin-protein ligase TRIM23

2

19

High-throughput

0.783

High

1077289

DLG2
Disks large homolog 2

2

7

High-throughput

0.783

High

1271029

DLG3
Disks large homolog 3

2

6

High-throughput

0.783

High

1046449

SNTB1
Beta-1-syntrophin

1

15

High-throughput

0.691

High

1335066

RHG35
Rho GTPase-activating protein 35

1

6

High-throughput

0.691

High

982515

1433F
14-3-3 protein eta

4

20

Small-scale

0.691

High

280074

MPDZ
Multiple PDZ domain protein

3

20

Small-scale

0.672

High

905128

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

158236

GIPC1
PDZ domain-containing protein GIPC1

3

4

High-throughput

0.653

High

910041

1433E
14-3-3 protein epsilon

2

13

High-throughput

0.628

High

927546

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.628

High

1335065

PKHA1
Pleckstrin homology domain-containing family A member 1

1

15

Small-scale

0.621

High

283034

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

9

High-throughput

0.618

High

350564

RASK
GTPase KRas

1

20

Small-scale

0.618

High

506420

RALA
Ras-related protein Ral-A

1

20

Small-scale

0.618

High

545627

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

Small-scale

0.618

High

845259

RAB7A
Ras-related protein Rab-7a

1

18

Small-scale

0.618

High

924876

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

647291

1433T
14-3-3 protein theta

2

20

Small-scale

0.611

High

809176

UTRN
Utrophin

2

7

Small-scale

0.611

High

1136610

FHL5
Four and a half LIM domains protein 5

2

10

High-throughput

0.606

High

1144782

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

13

High-throughput

0.606

High

1252488

LNX1
E3 ubiquitin-protein ligase LNX

2

16

High-throughput

0.606

High

1257220

GIPC2
PDZ domain-containing protein GIPC2

2

4

High-throughput

0.606

High

1298403

AP4AT
AP-4 complex accessory subunit Tepsin

2

1

High-throughput

0.606

High

1332629

EGLN3
Prolyl hydroxylase EGLN3

2

3

High-throughput

0.606

High

1335068

SNTG1
Gamma-1-syntrophin

2

17

High-throughput

0.606

High

1200439

URP2
Fermitin family homolog 3

1

0

Small-scale

0.586

High

1253315

M1AP
Meiosis 1 arrest protein

2

0

High-throughput

0.580

High

253194

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.553

High

995232

GOGA2
Golgin subfamily A member 2

2

9

High-throughput

0.553

High

1257214

GIPC3
PDZ domain-containing protein GIPC3

2

4

High-throughput

0.553

High

725566

COPB2
Coatomer subunit beta'

1

4

Small-scale

0.553

High

1296912

SNX27
Sorting nexin-27

1

17

High-throughput

0.553

High

1328146

RAB1B
Ras-related protein Rab-1B

1

8

Small-scale

0.553

High

216587

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.536

High

244959

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.536

High

246493

DTNB
Dystrobrevin beta

1

5

High-throughput

0.536

High

441374

RU2B
U2 small nuclear ribonucleoprotein B''

1

4

High-throughput

0.536

High

513896

DMD
Dystrophin

1

6

High-throughput

0.536

High

683725

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

749866

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.536

High

1157383

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

1

High-throughput

0.536

High

1333337

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

2

High-throughput

0.536

High

1335070

CTNL1
Alpha-catulin

1

5

High-throughput

0.536

High

1335072

DTNA
Dystrobrevin alpha

1

4

High-throughput

0.536

High

1020218

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

10

Small-scale

0.527

High

1107849

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.513

High

1330261

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.513

High

1335067

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.513

High

1293647

SAHH3
Adenosylhomocysteinase 3

1

1

High-throughput

0.489

High

225903

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

3

Small-scale

0.479

High

272282

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

3

Small-scale

0.479

High

321642

AP2A1
AP-2 complex subunit alpha-1

1

6

Small-scale

0.479

High

397514

ADT2
ADP/ATP translocase 2

1

2

Small-scale

0.479

High

401118

RLA0
Large ribosomal subunit protein uL10

1

1

Small-scale

0.479

High

518206

ADT1
ADP/ATP translocase 1

1

2

Small-scale

0.479

High

522202

CADH1
Cadherin-1

1

8

High-throughput

0.479

High

527802

LAMP2
Lysosome-associated membrane glycoprotein 2

1

9

Small-scale

0.479

High

614142

TBG1
Tubulin gamma-1 chain

1

3

Small-scale

0.479

High

665957

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

2

Small-scale

0.479

High

708773

MCM5
DNA replication licensing factor MCM5

1

2

Small-scale

0.479

High

709060

MCM7
DNA replication licensing factor MCM7

1

2

Small-scale

0.479

High

800077

VDAC2
Voltage-dependent anion-selective channel protein 2

1

1

Small-scale

0.479

High

864015

CLH2
Clathrin heavy chain 2

1

3

Small-scale

0.479

High

952131

SRSF3
Serine/arginine-rich splicing factor 3

1

2

Small-scale

0.479

High

960980

CLH1
Clathrin heavy chain 1

1

3

Small-scale

0.479

High

1029893

TIF1B
Transcription intermediary factor 1-beta

1

5

Small-scale

0.479

High

1060929

IMB1
Importin subunit beta-1

1

1

Small-scale

0.479

High

1082401

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.479

High

1171779

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1287576

GCP3
Gamma-tubulin complex component 3

1

2

Small-scale

0.479

High

1311276

GCP2
Gamma-tubulin complex component 2

1

2

Small-scale

0.479

High

1335069

TBA8
Tubulin alpha-8 chain

1

3

Small-scale

0.479

High

268529

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

354768

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

Small-scale

0.458

High

1058607

RFTN1
Raftlin

1

0

Small-scale

0.458

High

867129

SC24C
Protein transport protein Sec24C

1

1

Small-scale

0.437

High

1074006

SC23A
Protein transport protein Sec23A

1

1

Small-scale

0.437

High

1201913

TAXB1
Tax1-binding protein 1

1

13

High-throughput

0.437

High

1239740

NHLC2
NHL repeat-containing protein 2

1

2

High-throughput

0.437

High

1245190

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.437

High

1335071

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.316

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024