Protein: P2RY8
P2Y purinoceptor 8 (P2Y8)

Gene: P2RY8
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q86VZ1

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0035025 - positive regulation of Rho protein signal transduction
GO:0045028 - G protein-coupled purinergic nucleotide receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580435

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

3

20

High-throughput

0.861

High

837623

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

20

High-throughput

0.789

High

677601

NTR1
Neurotensin receptor type 1

1

17

High-throughput

0.691

High

738467

ACV1B
Activin receptor type-1B

1

1

High-throughput

0.691

High

565379

TMM11
Transmembrane protein 11, mitochondrial

3

4

High-throughput

0.667

High

843465

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

3

20

High-throughput

0.667

High

1045030

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

3

20

High-throughput

0.667

High

1086542

AT2B3
Plasma membrane calcium-transporting ATPase 3

3

20

High-throughput

0.667

High

1202695

LRC15
Leucine-rich repeat-containing protein 15

3

1

High-throughput

0.667

High

1202742

SERC1
Serine incorporator 1

3

8

High-throughput

0.667

High

1202737

GOLP3
Golgi phosphoprotein 3

2

2

High-throughput

0.628

High

331311

CHK2
Serine/threonine-protein kinase Chk2

1

2

High-throughput

0.618

High

1202685

VRK2
Serine/threonine-protein kinase VRK2

1

2

High-throughput

0.618

High

1202717

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

2

High-throughput

0.618

High

535454

GFAP
Glial fibrillary acidic protein

3

2

High-throughput

0.609

High

1031558

ATM
Serine-protein kinase ATM

3

20

High-throughput

0.609

High

1153810

ACD10
Acyl-CoA dehydrogenase family member 10

3

9

High-throughput

0.609

High

1202693

ATLA2
Atlastin-2

3

16

High-throughput

0.609

High

1202740

AT133
Polyamine-transporting ATPase 13A3

3

20

High-throughput

0.609

High

1202754

CS025
UPF0449 protein C19orf25

3

4

High-throughput

0.609

High

176614

FANCA
Fanconi anemia group A protein

2

6

High-throughput

0.558

High

304984

DUS14
Dual specificity protein phosphatase 14

2

1

High-throughput

0.558

High

371094

NU1M
NADH-ubiquinone oxidoreductase chain 1

2

2

High-throughput

0.558

High

1162189

BRAT1
BRCA1-associated ATM activator 1

2

6

High-throughput

0.558

High

1202686

DAAF5
Dynein axonemal assembly factor 5

2

7

High-throughput

0.558

High

1202726

FACD2
Fanconi anemia group D2 protein

2

10

High-throughput

0.558

High

1202734

METL9
Protein-L-histidine N-pros-methyltransferase

2

1

High-throughput

0.558

High

1202744

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

2

7

High-throughput

0.558

High

167958

NPC1
NPC intracellular cholesterol transporter 1

1

5

High-throughput

0.536

High

168188

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

8

High-throughput

0.536

High

173485

RER1
Protein RER1

1

3

High-throughput

0.536

High

174408

FANCG
Fanconi anemia group G protein

1

1

High-throughput

0.536

High

217182

EXTL3
Exostosin-like 3

1

1

High-throughput

0.536

High

392697

B3A2
Anion exchange protein 2

1

6

High-throughput

0.536

High

530923

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

20

High-throughput

0.536

High

588630

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

20

High-throughput

0.536

High

619255

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

20

High-throughput

0.536

High

792804

EAA3
Excitatory amino acid transporter 3

1

4

High-throughput

0.536

High

871927

AT12A
Potassium-transporting ATPase alpha chain 2

1

20

High-throughput

0.536

High

943733

PRAME
Melanoma antigen preferentially expressed in tumors

1

4

High-throughput

0.536

High

958300

AT2C1
Calcium-transporting ATPase type 2C member 1

1

20

High-throughput

0.536

High

965738

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.536

High

966830

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

20

High-throughput

0.536

High

1034230

S39A6
Zinc transporter ZIP6

1

20

High-throughput

0.536

High

1078801

MSMO1
Methylsterol monooxygenase 1

1

5

High-throughput

0.536

High

1137523

RIF1
Telomere-associated protein RIF1

1

5

High-throughput

0.536

High

1137730

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

10

High-throughput

0.536

High

1160133

S39A4
Zinc transporter ZIP4

1

20

High-throughput

0.536

High

1174997

TBA1A
Tubulin alpha-1A chain

1

8

High-throughput

0.536

High

1202694

CIP2A
Protein CIP2A

1

8

High-throughput

0.536

High

1202705

COQ8B
Atypical kinase COQ8B, mitochondrial

1

12

High-throughput

0.536

High

1202710

VMP1
Vacuole membrane protein 1

1

2

High-throughput

0.536

High

1202713

EXOC2
Exocyst complex component 2

1

9

High-throughput

0.536

High

1202718

CHP1
Calcineurin B homologous protein 1

1

1

High-throughput

0.536

High

1202721

S39A3
Zinc transporter ZIP3

1

20

High-throughput

0.536

High

1202728

ABCA2
ATP-binding cassette sub-family A member 2

1

1

High-throughput

0.536

High

1202731

YIPF3
Protein YIPF3

1

8

High-throughput

0.536

High

1202736

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

1

4

High-throughput

0.536

High

1202750

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

4

High-throughput

0.536

High

1202757

S39AA
Zinc transporter ZIP10

1

20

High-throughput

0.536

High

1202761

SC5A6
Sodium-dependent multivitamin transporter

1

3

High-throughput

0.536

High

528172

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.513

High

834310

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

1202752

ATX10
Ataxin-10

1

0

High-throughput

0.513

High

1136671

H37
Histone H3-7

2

3

High-throughput

0.504

High

163619

BTAF1
TATA-binding protein-associated factor 172

1

10

High-throughput

0.489

High

168555

SCAM2
Secretory carrier-associated membrane protein 2

1

7

High-throughput

0.489

High

175571

TM9S1
Transmembrane 9 superfamily member 1

1

14

High-throughput

0.489

High

178209

IPO8
Importin-8

1

20

High-throughput

0.489

High

195921

TTI1
TELO2-interacting protein 1 homolog

1

4

High-throughput

0.489

High

207960

XPOT
Exportin-T

1

20

High-throughput

0.489

High

212215

ERD23
ER lumen protein-retaining receptor 3

1

7

High-throughput

0.489

High

264587

MTX2
Metaxin-2

1

9

High-throughput

0.489

High

281728

WFS1
Wolframin

1

3

High-throughput

0.489

High

1202698

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

8

High-throughput

0.489

High

1202699

GCN1
Stalled ribosome sensor GCN1

1

20

High-throughput

0.489

High

1202700

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.489

High

1202701

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.489

High

1202702

YIPF5
Protein YIPF5

1

8

High-throughput

0.489

High

1202703

EVI5L
EVI5-like protein

1

9

High-throughput

0.489

High

1202704

F241B
Protein FAM241B

1

3

High-throughput

0.489

High

1202706

HOOK2
Protein Hook homolog 2

1

7

High-throughput

0.489

High

1202707

SAAL1
Protein SAAL1

1

3

High-throughput

0.489

High

1202708

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

5

High-throughput

0.489

High

295740

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

2

High-throughput

0.489

High

297181

IPO13
Importin-13

1

20

High-throughput

0.489

High

318498

CDS2
Phosphatidate cytidylyltransferase 2

1

1

High-throughput

0.489

High

321338

STR3N
STARD3 N-terminal-like protein

1

1

High-throughput

0.489

High

335683

COX1
Cytochrome c oxidase subunit 1

1

3

High-throughput

0.489

High

373132

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

5

High-throughput

0.489

High

622688

ERD21
ER lumen protein-retaining receptor 1

1

7

High-throughput

0.489

High

702621

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

3

High-throughput

0.489

High

787517

MTOR
Serine/threonine-protein kinase mTOR

1

20

High-throughput

0.489

High

881640

PEX3
Peroxisomal biogenesis factor 3

1

2

High-throughput

0.489

High

884030

GEMI4
Gem-associated protein 4

1

5

High-throughput

0.489

High

975384

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

5

High-throughput

0.489

High

976738

TAP1
Antigen peptide transporter 1

1

10

High-throughput

0.489

High

1067319

OXA1L
Mitochondrial inner membrane protein OXA1L

1

4

High-throughput

0.489

High

1088551

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.489

High

1121738

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

20

High-throughput

0.489

High

1124730

YIF1B
Protein YIF1B

1

4

High-throughput

0.489

High

1125852

PIGG
GPI ethanolamine phosphate transferase 2

1

7

High-throughput

0.489

High

1126212

RABL3
Rab-like protein 3

1

5

High-throughput

0.489

High

1130888

TM201
Transmembrane protein 201

1

2

High-throughput

0.489

High

1132553

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

4

High-throughput

0.489

High

1138692

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.489

High

1139392

ECM29
Proteasome adapter and scaffold protein ECM29

1

20

High-throughput

0.489

High

1150139

ATLA3
Atlastin-3

1

16

High-throughput

0.489

High

1157060

ARMC6
Armadillo repeat-containing protein 6

1

4

High-throughput

0.489

High

1159555

TTC27
Tetratricopeptide repeat protein 27

1

3

High-throughput

0.489

High

1161393

SKI3
Superkiller complex protein 3

1

1

High-throughput

0.489

High

1168062

THADA
tRNA

1

7

High-throughput

0.489

High

1185306

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

20

High-throughput

0.489

High

1186173

DYM
Dymeclin

1

8

High-throughput

0.489

High

1187492

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

8

High-throughput

0.489

High

1188026

SETX
Probable helicase senataxin

1

1

High-throughput

0.489

High

1189532

MON2
Protein MON2 homolog

1

20

High-throughput

0.489

High

1199730

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

7

High-throughput

0.489

High

1202687

ZDH17
Palmitoyltransferase ZDHHC17

1

9

High-throughput

0.489

High

1202688

K2013
Uncharacterized protein KIAA2013

1

6

High-throughput

0.489

High

1202689

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

5

High-throughput

0.489

High

1202690

INT1
Integrator complex subunit 1

1

10

High-throughput

0.489

High

1202692

ZNT7
Zinc transporter 7

1

13

High-throughput

0.489

High

1202696

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

15

High-throughput

0.489

High

1202697

TM9S4
Transmembrane 9 superfamily member 4

1

14

High-throughput

0.489

High

1202711

RN185
E3 ubiquitin-protein ligase RNF185

1

8

High-throughput

0.489

High

1202712

RUSF1
RUS family member 1

1

5

High-throughput

0.489

High

1202714

MBOA7
Lysophospholipid acyltransferase 7

1

9

High-throughput

0.489

High

1202715

CP2S1
Cytochrome P450 2S1

1

3

High-throughput

0.489

High

1202716

SEC62
Translocation protein SEC62

1

3

High-throughput

0.489

High

1202719

SGMR1
Sigma non-opioid intracellular receptor 1

1

6

High-throughput

0.489

High

1202720

MIC25
MICOS complex subunit MIC25

1

1

High-throughput

0.489

High

1202722

GCP2
Gamma-tubulin complex component 2

1

18

High-throughput

0.489

High

1202723

DERL1
Derlin-1

1

6

High-throughput

0.489

High

1202724

PTSS2
Phosphatidylserine synthase 2

1

7

High-throughput

0.489

High

1202729

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

1

High-throughput

0.489

High

1202730

XPO4
Exportin-4

1

20

High-throughput

0.489

High

1202732

DERL2
Derlin-2

1

6

High-throughput

0.489

High

1202733

INT2
Integrator complex subunit 2

1

4

High-throughput

0.489

High

1202735

SPNS1
Protein spinster homolog 1

1

1

High-throughput

0.489

High

1202738

HEAT1
HEAT repeat-containing protein 1

1

6

High-throughput

0.489

High

1202739

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

2

High-throughput

0.489

High

1202741

COG4
Conserved oligomeric Golgi complex subunit 4

1

5

High-throughput

0.489

High

1202743

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.489

High

1202745

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

5

High-throughput

0.489

High

1202746

ECHD1
Ethylmalonyl-CoA decarboxylase

1

5

High-throughput

0.489

High

1202747

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

12

High-throughput

0.489

High

1202748

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

7

High-throughput

0.489

High

1202749

FANCI
Fanconi anemia group I protein

1

2

High-throughput

0.489

High

1202753

FA8A1
Protein FAM8A1

1

1

High-throughput

0.489

High

1202756

IPO11
Importin-11

1

20

High-throughput

0.489

High

1202758

TMCO1
Calcium load-activated calcium channel

1

6

High-throughput

0.489

High

1202759

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

4

High-throughput

0.489

High

1202760

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

6

High-throughput

0.489

High

1202762

C2CD2
C2 domain-containing protein 2

1

1

High-throughput

0.489

High

1202763

TELO2
Telomere length regulation protein TEL2 homolog

1

4

High-throughput

0.489

High

1202765

TNPO3
Transportin-3

1

20

High-throughput

0.489

High

1202766

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

7

High-throughput

0.489

High

1202767

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

20

High-throughput

0.489

High

1117762

Q4LE69
1-phosphatidylinositol 4-kinase

1

16

High-throughput

0.479

High

1123278

PKHG4
Puratrophin-1

1

5

High-throughput

0.479

High

1197729

DSG4
Desmoglein-4

1

3

High-throughput

0.479

High

1202727

HYCCI
Hyccin

1

2

High-throughput

0.479

High

787661

PI4KA
Phosphatidylinositol 4-kinase alpha

1

18

High-throughput

0.445

High

764659

CUX1
Homeobox protein cut-like 1

1

7

High-throughput

0.437

High

1202751

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

7

High-throughput

0.437

High

1047392

CASP
Protein CASP

1

7

High-throughput

0.407

High

253791

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.279

Low

653153

DCK
Deoxycytidine kinase

1

0

High-throughput

0.279

Low

993106

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.279

Low

1013974

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

1188478

GLUCM
D-glutamate cyclase, mitochondrial

1

0

High-throughput

0.279

Low

1202684

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.279

Low

1202691

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.279

Low

1202709

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.279

Low

1202725

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1202755

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.279

Low

1202764

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024