Protein: SIX5
Homeobox protein SIX5 (DM locus-associated homeodomain protein) (Sine oculis homeobox homolog 5)

Gene: SIX5
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q8N196

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002088 - lens development in camera-type eye

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1230645

EYA3
Eyes absent homolog 3

2

20

Small-scale

0.789

High

318670

EYA4
Eyes absent homolog 4

1

20

High-throughput

0.691

High

1230644

EYA1
Eyes absent homolog 1

1

20

High-throughput

0.691

High

515607

SRF
Serum response factor

1

3

High-throughput

0.618

High

868600

ATX1
Ataxin-1

1

0

High-throughput

0.549

High

176235

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.536

High

267176

GEMI
Geminin

1

1

High-throughput

0.536

High

1021321

FOXL1
Forkhead box protein L1

1

7

High-throughput

0.536

High

1050709

FHL2
Four and a half LIM domains protein 2

1

4

High-throughput

0.536

High

1230639

STK40
Serine/threonine-protein kinase 40

1

2

High-throughput

0.536

High

1230640

COP1
E3 ubiquitin-protein ligase COP1

1

5

High-throughput

0.536

High

1230642

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

3

High-throughput

0.536

High

1230647

FOXB1
Forkhead box protein B1

1

7

High-throughput

0.536

High

1230650

MTMR4
Myotubularin-related protein 4

1

1

High-throughput

0.536

High

1230651

DICER
Endoribonuclease Dicer

1

2

High-throughput

0.536

High

1069419

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1185060

DET1
DET1 homolog

1

0

High-throughput

0.513

High

1230641

ARK2N
Protein ARK2N

1

0

High-throughput

0.513

High

1230648

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.513

High

1230649

DIAP3
Protein diaphanous homolog 3

1

0

High-throughput

0.513

High

1219782

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

6

High-throughput

0.489

High

1230643

TCPQM
T-complex protein 1 subunit theta-like 2

1

5

High-throughput

0.489

High

1230646

FEV
Protein FEV

1

7

High-throughput

0.479

High

217913

PRKY
Putative serine/threonine-protein kinase PRKY

1

3

High-throughput

0.445

High


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Last updated: 15 Jul 2024