Protein: MCF2L
Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein)

Gene: MCF2L
Organism: Homo sapiens
Interactions: 20
UniProt ID: O15068

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

176738

CDC42
Cell division control protein 42 homolog

4

20

Small-scale

0.893

High

176742

RAC1
Ras-related C3 botulinum toxin substrate 1

4

20

Small-scale

0.882

High

176739

RHOA
Transforming protein RhoA

2

20

Small-scale

0.755

High

176747

KPCD2
Serine/threonine-protein kinase D2

1

11

High-throughput

0.618

High

176736

ENPL
Endoplasmin

1

4

High-throughput

0.515

High

176743

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.486

High

176749

YAE1
Protein YAE1 homolog

1

0

High-throughput

0.486

High

176751

PRAF1
Prenylated Rab acceptor protein 1

1

0

High-throughput

0.486

High

176735

GCR
Glucocorticoid receptor

1

14

High-throughput

0.479

High

176741

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

6

Small-scale

0.479

High

176744

CUL4B
Cullin-4B

1

12

High-throughput

0.479

High

176745

SMAD2
Mothers against decapentaplegic homolog 2

1

3

High-throughput

0.479

High

176748

SLK
STE20-like serine/threonine-protein kinase

1

19

High-throughput

0.479

High

176734

WFS1
Wolframin

1

1

High-throughput

0.470

High

176733

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

176737

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

176750

DISC1
Disrupted in schizophrenia 1 protein

1

8

High-throughput

0.457

High

176752

AGO1
Protein argonaute-1

1

2

High-throughput

0.445

High

176746

FKB15
FK506-binding protein 15

1

10

High-throughput

0.417

High

176740

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025