Protein: PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) [Includes: Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC); Phosphoribosylaminoimidazole succinocarboxamide synthetase (EC 6.3.2.6) (SAICAR synthetase)]

Gene: PUR6, Paics
Organism: Mus musculus
Interactions: 15
UniProt ID: Q9DCL9

Gene Ontology (top 5):
GO:0004638 - phosphoribosylaminoimidazole carboxylase activity
GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006177 - GMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1297904

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

205135

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.458

High

928066

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

1021655

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.458

High

1189124

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

1191232

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

High-throughput

0.458

High

1408678

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.458

High

1298522

FTM
Protein fantom

1

1

High-throughput

0.445

High

1221545

TRAF3
TNF receptor-associated factor 3

1

2

Small-scale

0.437

High

1283426

WDTC1
WD and tetratricopeptide repeats protein 1

1

1

High-throughput

0.437

High

1298361

MT21E
Protein-lysine methyltransferase METTL21E

1

1

High-throughput

0.437

High

1423633

ASB11
Ankyrin repeat and SOCS box protein 11

1

3

High-throughput

0.437

High

1221847

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.249

Low

1282610

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.249

Low

1362734

EED
Polycomb protein EED

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025