Protein: SMYD4
Protein-lysine N-methyltransferase SMYD4 (EC 2.1.1.-) (SET and MYND domain-containing protein 4)

Gene: SMYD4
Organism: Homo sapiens
Interactions: 16
UniProt ID: Q8IYR2

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007507 - heart development
GO:0008168 - methyltransferase activity
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1161935

H31T
Histone H3.1t

1

12

High-throughput

0.665

High

438091

GLPB
Glycophorin-B

2

3

High-throughput

0.574

High

351135

ECD
Protein ecdysoneless homolog

1

1

High-throughput

0.536

High

521800

H14
Histone H1.4

1

1

High-throughput

0.536

High

996762

TBA1B
Tubulin alpha-1B chain

1

8

High-throughput

0.536

High

1315396

NPAS1
Neuronal PAS domain-containing protein 1

1

6

High-throughput

0.536

High

1315397

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.513

High

508261

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

869913

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.493

High

1315395

TCPQM
T-complex protein 1 subunit theta-like 2

1

4

High-throughput

0.489

High

1201268

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.458

High

372537

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.445

High

1315393

GMCL2
Germ cell-less protein-like 2

1

5

High-throughput

0.445

High

231602

PRKY
Putative serine/threonine-protein kinase PRKY

1

4

High-throughput

0.407

High

1315398

S27A6
Long-chain fatty acid transport protein 6

1

7

High-throughput

0.407

High

1315394

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025