Protein: PIAS3
E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3)

Gene: PIAS3
Organism: Mus musculus
Interactions: 9
UniProt ID: O54714

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0010629 - negative regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

236336

SUMO1
Small ubiquitin-related modifier 1

1

20

Small-scale

0.713

High

236337

UBC9
SUMO-conjugating enzyme UBC9

1

14

Small-scale

0.713

High

236338

GFI1
Zinc finger protein Gfi-1

2

2

Small-scale

0.619

High

236333

IRF1
Interferon regulatory factor 1

1

3

Small-scale

0.573

High

236334

TBP
TATA-box-binding protein

1

1

Small-scale

0.552

High

236340

TF65
Transcription factor p65

1

7

High-throughput

0.481

High

236341

MITF
Microphthalmia-associated transcription factor

1

6

High-throughput

0.481

High

236335

STAT3
Signal transducer and activator of transcription 3

1

5

Small-scale

0.479

High

236339

IKZF1
DNA-binding protein Ikaros

1

2

Small-scale

0.479

High


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Last updated: 11Aug2025