Protein: FCG2B
Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32)

Gene: FCG2B, FCGR2B
Organism: Homo sapiens
Interactions: 25
UniProt ID: P31994

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001788 - antibody-dependent cellular cytotoxicity
GO:0001811 - negative regulation of type I hypersensitivity
GO:0001814 - negative regulation of antibody-dependent cellular cytotoxicity
GO:0001818 - negative regulation of cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

519369

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

3

16

High-throughput

0.861

High

353642

IGHG1
Immunoglobulin heavy constant gamma 1

1

7

Small-scale

0.692

High

685209

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

5

7

Small-scale

0.692

High

665804

PTN6
Tyrosine-protein phosphatase non-receptor type 6

3

19

Small-scale

0.656

High

685206

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

19

Small-scale

0.639

High

685204

GSK3A
Glycogen synthase kinase-3 alpha

3

5

High-throughput

0.609

High

433610

LYN
Tyrosine-protein kinase Lyn

2

19

Small-scale

0.585

High

666011

SHC1
SHC-transforming protein 1

2

20

Small-scale

0.571

High

685205

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.563

High

580945

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

High-throughput

0.561

High

411317

INSR
Insulin receptor

1

7

High-throughput

0.515

High

566302

KPCA
Protein kinase C alpha type

1

5

Small-scale

0.501

High

658807

MK01
Mitogen-activated protein kinase 1

1

4

Small-scale

0.501

High

572293

LEG3
Galectin-3

1

1

Small-scale

0.500

High

241149

TOM1
Target of Myb1 membrane trafficking protein

1

2

Small-scale

0.479

High

412047

FYN
Tyrosine-protein kinase Fyn

1

19

High-throughput

0.479

High

522811

SRC
Proto-oncogene tyrosine-protein kinase Src

1

19

High-throughput

0.479

High

557621

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

685203

CRK
Adapter molecule crk

1

19

High-throughput

0.479

High

685210

KLK6
Kallikrein-6

1

3

High-throughput

0.470

High

243132

SH21A
SH2 domain-containing protein 1A

1

20

Small-scale

0.437

High

685207

GAB1
GRB2-associated-binding protein 1

1

2

Small-scale

0.373

High

685211

SYMM
Methionine--tRNA ligase, mitochondrial

3

0

High-throughput

0.347

High

685208

CRYM
Ketimine reductase mu-crystallin

1

0

High-throughput

0.279

Low

685212

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024