Protein: PTGR1
Prostaglandin reductase 1 (PRG-1) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (Dithiolethione-inducible gene 1 protein) (D3T-inducible gene 1 protein) (DIG-1) (Leukotriene B4 12-hydroxydehydrogenase) (NAD(P)H-dependent alkenal/one oxidoreductase) (EC 1.3.1.74)

Gene: PTGR1
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q14914

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006691 - leukotriene metabolic process
GO:0006693 - prostaglandin metabolic process
GO:0035798 - 2-alkenal reductase (NADPH) activity
GO:0036102 - leukotriene B4 metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1133342

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.536

High

241704

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

537178

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

1114823

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1133339

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1133343

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

482480

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

567400

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

1133337

FSCN1
Fascin

1

0

High-throughput

0.458

High

259960

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

332104

MRP6
ATP-binding cassette sub-family C member 6

1

3

Small-scale

0.437

High

353331

AGR2
Anterior gradient protein 2 homolog

1

3

Small-scale

0.437

High

261173

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.407

High

1103960

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

608269

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1133340

ZN687
Zinc finger protein 687

1

0

High-throughput

0.279

Low

1133341

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1133338

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025