Protein: MRP6
ATP-binding cassette sub-family C member 6 (EC 7.6.2.-) (EC 7.6.2.3) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter E) (MOAT-E) (Multidrug resistance-associated protein 6)

Gene: MRP6, ABCC6
Organism: Homo sapiens
Interactions: 59
UniProt ID: O95255

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

332065

MRP6
ATP-binding cassette sub-family C member 6

1

9

Small-scale

0.618

High

332072

RLA0
Large ribosomal subunit protein uL10

1

1

Small-scale

0.618

High

270749

ROCK2
Rho-associated protein kinase 2

1

0

Small-scale

0.586

High

332105

ZMY11
Zinc finger MYND domain-containing protein 11

1

1

High-throughput

0.501

High

332070

A1BG
Alpha-1B-glycoprotein

1

1

High-throughput

0.481

High

332075

FURIN
Furin

1

1

High-throughput

0.481

High

332081

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

7

High-throughput

0.481

High

332093

KAD2
Adenylate kinase 2, mitochondrial

1

1

High-throughput

0.481

High

133906

IPO5
Importin-5

1

4

Small-scale

0.479

High

323812

SC31A
Protein transport protein Sec31A

1

1

Small-scale

0.479

High

332067

PGK1
Phosphoglycerate kinase 1

1

1

Small-scale

0.479

High

332069

GCR
Glucocorticoid receptor

1

7

High-throughput

0.479

High

332074

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

Small-scale

0.479

High

332077

BIP
Endoplasmic reticulum chaperone BiP

1

1

Small-scale

0.479

High

332079

EZRI
Ezrin

1

4

Small-scale

0.479

High

332082

CALR
Calreticulin

1

6

Small-scale

0.479

High

332083

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

1

Small-scale

0.479

High

332089

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

Small-scale

0.479

High

332091

COPB
Coatomer subunit beta

1

2

Small-scale

0.479

High

332092

COPA
Coatomer subunit alpha

1

1

Small-scale

0.479

High

332100

CLH1
Clathrin heavy chain 1

1

3

Small-scale

0.479

High

332108

GCN1
Stalled ribosome sensor GCN1

1

5

Small-scale

0.479

High

332110

EXOS8
Exosome complex component RRP43

1

2

Small-scale

0.479

High

332111

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

Small-scale

0.479

High

332068

A2MG
Alpha-2-macroglobulin

1

0

Small-scale

0.458

High

332071

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

0

Small-scale

0.458

High

332073

PDIA1
Protein disulfide-isomerase

1

0

Small-scale

0.458

High

332076

MGST1
Microsomal glutathione S-transferase 1

1

0

Small-scale

0.458

High

332080

CEBPB
CCAAT/enhancer-binding protein beta

1

0

Small-scale

0.458

High

332087

RL27A
Large ribosomal subunit protein uL15

1

0

Small-scale

0.458

High

332088

GDIB
Rab GDP dissociation inhibitor beta

1

0

Small-scale

0.458

High

332094

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

Small-scale

0.458

High

332095

RS15A
Small ribosomal subunit protein uS8

1

0

Small-scale

0.458

High

332096

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

Small-scale

0.458

High

332097

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

Small-scale

0.458

High

332099

RS28
Small ribosomal subunit protein eS28

1

0

Small-scale

0.458

High

332101

RL6
Large ribosomal subunit protein eL6

1

0

Small-scale

0.458

High

332107

CSN6
COP9 signalosome complex subunit 6

1

0

Small-scale

0.458

High

332112

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

1

High-throughput

0.457

High

332114

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

1

High-throughput

0.457

High

332085

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

332117

CRYL1
Lambda-crystallin homolog

1

1

High-throughput

0.439

High

209409

SERA
D-3-phosphoglycerate dehydrogenase

1

1

Small-scale

0.437

High

332066

AL1A1
Aldehyde dehydrogenase 1A1

1

1

Small-scale

0.437

High

332086

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

Small-scale

0.437

High

332102

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

2

Small-scale

0.437

High

332104

PTGR1
Prostaglandin reductase 1

1

3

Small-scale

0.437

High

332115

GHC1
Mitochondrial glutamate carrier 1

1

1

Small-scale

0.437

High

332078

AK1A1
Aldo-keto reductase family 1 member A1

1

0

Small-scale

0.249

Low

332084

PRDX2
Peroxiredoxin-2

1

0

Small-scale

0.249

Low

332090

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

0

Small-scale

0.249

Low

332098

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

0

Small-scale

0.249

Low

332103

GALE
UDP-glucose 4-epimerase

1

0

Small-scale

0.249

Low

332106

QNG1
Queuosine 5'-phosphate N-glycosylase/hydrolase

1

0

Small-scale

0.249

Low

332109

MYDGF
Myeloid-derived growth factor

1

0

Small-scale

0.249

Low

332113

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

Small-scale

0.249

Low

332116

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

Small-scale

0.249

Low

332118

SERC
Phosphoserine aminotransferase

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025