Protein: PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16, EC 3.1.3.48)

Gene: PTPM1, PTPMT1
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q8WUK0

Gene Ontology (top 5):
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1260291

CLPB
Mitochondrial disaggregase

2

3

High-throughput

0.754

High

1260275

MDFI
MyoD family inhibitor

4

1

High-throughput

0.703

High

283227

RGS20
Regulator of G-protein signaling 20

4

1

High-throughput

0.700

High

1260279

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

3

1

High-throughput

0.667

High

1085448

MK06
Mitogen-activated protein kinase 6

1

20

High-throughput

0.656

High

794407

GRK6
G protein-coupled receptor kinase 6

1

2

High-throughput

0.618

High

1200396

ST32C
Serine/threonine-protein kinase 32C

1

3

High-throughput

0.618

High

1238097

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

16

High-throughput

0.618

High

300786

GLSK
Glutaminase kidney isoform, mitochondrial

1

4

High-throughput

0.618

High

1088025

DUS6
Dual specificity protein phosphatase 6

1

16

High-throughput

0.618

High

1260260

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

16

High-throughput

0.618

High

1260308

PAK5
Serine/threonine-protein kinase PAK 5

1

2

High-throughput

0.618

High

642122

KRA59
Keratin-associated protein 5-9

3

10

High-throughput

0.616

High

889348

KR107
Keratin-associated protein 10-7

3

8

High-throughput

0.616

High

889600

KR108
Keratin-associated protein 10-8

3

9

High-throughput

0.616

High

1071302

K1H1
Keratin, type I cuticular Ha1

3

3

High-throughput

0.616

High

1260286

KRA92
Keratin-associated protein 9-2

3

10

High-throughput

0.616

High

1260288

XPO4
Exportin-4

2

3

High-throughput

0.611

High

856749

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

815406

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

2

0

High-throughput

0.585

High

1189375

NT2NA
Notch homolog 2 N-terminal-like protein A

2

1

High-throughput

0.578

High

527663

LAMP2
Lysosome-associated membrane glycoprotein 2

2

1

High-throughput

0.574

High

868010

VMAT1
Chromaffin granule amine transporter

2

3

High-throughput

0.574

High

1056224

I13R2
Interleukin-13 receptor subunit alpha-2

2

7

High-throughput

0.574

High

536951

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.573

High

1127085

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

6

High-throughput

0.573

High

1216674

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.573

High

1086677

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

1260261

NU133
Nuclear pore complex protein Nup133

2

2

High-throughput

0.558

High

280668

KRT34
Keratin, type I cuticular Ha4

2

3

High-throughput

0.553

High

889847

KR109
Keratin-associated protein 10-9

2

9

High-throughput

0.553

High

1154158

KRA57
Keratin-associated protein 5-7

2

9

High-throughput

0.553

High

1216357

KRA13
Keratin-associated protein 1-3

2

11

High-throughput

0.553

High

1260278

KR412
Keratin-associated protein 4-12

2

11

High-throughput

0.553

High

1260285

KRA93
Keratin-associated protein 9-3

2

10

High-throughput

0.553

High

163900

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

3

High-throughput

0.536

High

420752

KLK1
Kallikrein-1

1

1

High-throughput

0.536

High

801270

KI67
Proliferation marker protein Ki-67

1

4

High-throughput

0.536

High

1053098

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

9

High-throughput

0.536

High

1260299

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

1

4

High-throughput

0.536

High

473325

KRA23
Keratin-associated protein 2-3

1

10

High-throughput

0.523

High

1149253

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.523

High

263946

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.513

High

1246604

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.513

High

1260290

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

62159

RCCD1
RCC1 domain-containing protein 1

1

3

High-throughput

0.489

High

365000

FRIL
Ferritin light chain

1

1

High-throughput

0.489

High

561639

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

High-throughput

0.489

High

985368

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.489

High

1260273

IPO9
Importin-9

1

13

High-throughput

0.489

High

208616

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

1

High-throughput

0.479

High

228170

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

264972

MPPB
Mitochondrial-processing peptidase subunit beta

1

6

High-throughput

0.479

High

279163

ATP5H
ATP synthase subunit d, mitochondrial

1

1

High-throughput

0.479

High

440636

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

577047

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

5

High-throughput

0.479

High

594937

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.479

High

610891

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

6

High-throughput

0.479

High

620681

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

1

High-throughput

0.479

High

668852

PML
Protein PML

1

5

High-throughput

0.479

High

726327

BASI
Basigin

1

7

High-throughput

0.479

High

736003

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.479

High

779800

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

789893

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

13

High-throughput

0.479

High

816052

ATPO
ATP synthase subunit O, mitochondrial

1

1

High-throughput

0.479

High

855517

MSH6
DNA mismatch repair protein Msh6

1

5

High-throughput

0.479

High

858296

TXTP
Tricarboxylate transport protein, mitochondrial

1

1

High-throughput

0.479

High

874549

XPO2
Exportin-2

1

10

High-throughput

0.479

High

877812

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

900734

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

959265

S25A3
Solute carrier family 25 member 3

1

3

High-throughput

0.479

High

990201

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1020498

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

1022556

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

High-throughput

0.479

High

1057333

SMC1A
Structural maintenance of chromosomes protein 1A

1

8

High-throughput

0.479

High

1064521

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1074485

SKI2
Superkiller complex protein 2

1

7

High-throughput

0.479

High

1088574

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

1114319

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.479

High

1126331

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

1

High-throughput

0.479

High

1242965

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1260265

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.479

High

1260266

TNPO1
Transportin-1

1

10

High-throughput

0.479

High

1260268

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1260269

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1260270

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.479

High

1260281

TMM70
Transmembrane protein 70, mitochondrial

1

3

High-throughput

0.479

High

1260284

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1260289

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1260292

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

2

High-throughput

0.479

High

1260296

HEAT1
HEAT repeat-containing protein 1

1

2

High-throughput

0.479

High

1260297

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

2

High-throughput

0.479

High

1260298

SFXN1
Sideroflexin-1

1

2

High-throughput

0.479

High

1260304

ATD3A
ATPase family AAA domain-containing protein 3A

1

7

High-throughput

0.479

High

1260305

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1260310

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.479

High

1260311

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1260312

STML2
Stomatin-like protein 2, mitochondrial

1

4

High-throughput

0.479

High

1260313

DICER
Endoribonuclease Dicer

1

11

High-throughput

0.479

High

1260314

SMC3
Structural maintenance of chromosomes protein 3

1

7

High-throughput

0.479

High

1260316

PDIP2
Polymerase delta-interacting protein 2

1

3

High-throughput

0.479

High

1260319

TELO2
Telomere length regulation protein TEL2 homolog

1

2

High-throughput

0.479

High

1260320

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

5

High-throughput

0.479

High

1260321

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

1260322

MTCH2
Mitochondrial carrier homolog 2

1

9

High-throughput

0.479

High

484674

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

1077915

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.464

High

258494

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

266765

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

282101

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

1

0

High-throughput

0.458

High

307402

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.458

High

486585

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

542540

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.458

High

579574

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.458

High

623309

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

0

High-throughput

0.458

High

777651

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

851949

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.458

High

878785

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

1

0

High-throughput

0.458

High

880458

ATP5E
ATP synthase subunit epsilon, mitochondrial

1

0

High-throughput

0.458

High

958487

CYC
Cytochrome c

1

0

High-throughput

0.458

High

1038222

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

Small-scale

0.458

High

1067328

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.458

High

1074620

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1128192

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1148689

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1183175

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1230585

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

1

0

High-throughput

0.458

High

1260267

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1260272

ATPMK
ATP synthase membrane subunit K, mitochondrial

1

0

High-throughput

0.458

High

1260274

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1260276

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

1260277

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.458

High

1260280

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1260294

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1260300

HINT3
Adenosine 5'-monophosphoramidase HINT3

1

0

High-throughput

0.458

High

1260307

CISD1
CDGSH iron-sulfur domain-containing protein 1

1

0

High-throughput

0.458

High

1260318

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.458

High

1260323

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

347426

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.445

High

888945

KR103
Keratin-associated protein 10-3

1

10

High-throughput

0.439

High

991631

KRA11
Keratin-associated protein 1-1

1

9

High-throughput

0.439

High

178232

IPO8
Importin-8

1

10

High-throughput

0.437

High

207971

XPOT
Exportin-T

1

12

High-throughput

0.437

High

234839

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

2

High-throughput

0.437

High

296957

LTN1
E3 ubiquitin-protein ligase listerin

1

2

High-throughput

0.437

High

320370

SNP29
Synaptosomal-associated protein 29

1

1

High-throughput

0.437

High

858018

NUP98
Nuclear pore complex protein Nup98-Nup96

1

3

High-throughput

0.437

High

951185

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.437

High

1015922

NU160
Nuclear pore complex protein Nup160

1

1

High-throughput

0.437

High

1189544

MON2
Protein MON2 homolog

1

1

High-throughput

0.437

High

1260263

GCN1
Stalled ribosome sensor GCN1

1

15

High-throughput

0.437

High

1260264

NU205
Nuclear pore complex protein Nup205

1

5

High-throughput

0.437

High

1260295

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1260301

ANLN
Anillin

1

1

High-throughput

0.437

High

1260302

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

1260309

ATX10
Ataxin-10

1

1

High-throughput

0.437

High

1260315

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

2

High-throughput

0.437

High

1260317

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

326336

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

2

0

High-throughput

0.328

High

67251

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

660639

GRN
Progranulin

2

0

High-throughput

0.316

High

888600

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

1135703

LCE2C
Late cornified envelope protein 2C

2

0

High-throughput

0.316

High

1166941

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

1260287

KRA31
Keratin-associated protein 3-1

2

0

High-throughput

0.316

High

1260303

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

245259

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

516094

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

792818

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.279

Low

1233006

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1254393

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.279

Low

1260262

AQP3
Aquaporin-3

1

0

High-throughput

0.279

Low

1260293

CAD23
Cadherin-23

1

0

High-throughput

0.279

Low

587

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

1259562

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

0

High-throughput

0.251

Low

537222

CX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial

1

0

High-throughput

0.249

Low

866978

MOT1
Monocarboxylate transporter 1

1

0

High-throughput

0.249

Low

1053615

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1101191

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1165792

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1260271

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1260282

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.249

Low

1260283

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.249

Low

1260306

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024