Protein: DKK4
Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form]

Gene: DKK4
Organism: Homo sapiens
Interactions: 9
UniProt ID: Q9UBT3

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0016055 - Wnt signaling pathway
GO:0030178 - negative regulation of Wnt signaling pathway
GO:0039706 - co-receptor binding
GO:0048019 - receptor antagonist activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

274929

LRP5
Low-density lipoprotein receptor-related protein 5

2

8

High-throughput

0.726

High

539501

ITAM
Integrin alpha-M

2

0

High-throughput

0.580

High

575212

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.536

High

1386617

OPTN
Optineurin

1

1

High-throughput

0.470

High

1437740

RNPL1
Aminopeptidase RNPEPL1

2

0

High-throughput

0.328

High

1216457

TSPO2
Translocator protein 2

2

0

High-throughput

0.316

High

1390251

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

1112760

CUL1
Cullin-1

1

0

High-throughput

0.279

Low

1311184

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025