Protein: GSDMD
Gasdermin-D (Gasdermin domain-containing protein 1) [Cleaved into: Gasdermin-D, N-terminal (GSDMD-NT) (hGSDMD-NTD); Gasdermin-D, C-terminal (GSDMD-CT) (hGSDMD-CTD); Gasdermin-D, p13 (Gasdermin-D, 13 kDa) (13 kDa GSDMD); Gasdermin-D, p40]

Gene: GSDMD
Organism: Homo sapiens
Interactions: 23
UniProt ID: P57764

Gene Ontology (top 5):
GO:0001786 - phosphatidylserine binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

667446

CASP1
Caspase-1

1

3

Small-scale

0.777

High

830275

CASP4
Caspase-4

1

3

Small-scale

0.692

High

884991

KCTD6
BTB/POZ domain-containing protein KCTD6

4

0

High-throughput

0.668

High

884984

CASP8
Caspase-8

1

3

Small-scale

0.618

High

884992

ZN558
Zinc finger protein 558

2

1

High-throughput

0.606

High

637374

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

884988

KAISO
Transcriptional regulator Kaiso

2

0

High-throughput

0.580

High

884990

LPP60
60 kDa lysophospholipase

2

0

High-throughput

0.580

High

884994

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

1

High-throughput

0.536

High

431705

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.479

High

438036

HS90B
Heat shock protein HSP 90-beta

1

1

Small-scale

0.479

High

600544

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.479

High

884989

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

Small-scale

0.479

High

884986

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

311682

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

Small-scale

0.458

High

352993

IL1B
Interleukin-1 beta

1

0

Small-scale

0.458

High

808065

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.458

High

884985

CDC37
Hsp90 co-chaperone Cdc37

1

0

Small-scale

0.458

High

884995

IRAK3
Interleukin-1 receptor-associated kinase 3

1

0

Small-scale

0.458

High

528851

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

837889

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

884987

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

884993

ZN426
Zinc finger protein 426

2

0

High-throughput

0.316

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024