HitPredict - High confidence protein-protein interactions

Protein: SORL
Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)

Gene: SORL, Sorl1
Organism: Mus musculus
Interactions: 9
UniProt ID: O88307

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001540 - amyloid-beta binding
GO:0002024 - diet induced thermogenesis
GO:0004888 - transmembrane signaling receptor activity
GO:0005615 - extracellular space

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
312043	A4 Amyloid-beta precursor protein	2	15	Small-scale	0.730	High
312044	INSR Insulin receptor	1	20	Small-scale	0.618	High
312045	NTRK2 BDNF/NT-3 growth factors receptor	1	17	Small-scale	0.618	High
312047	ERBB2 Receptor tyrosine-protein kinase erbB-2	1	20	Small-scale	0.618	High
312048	EGFR Epidermal growth factor receptor	1	20	Small-scale	0.618	High
312049	EPHA4 Ephrin type-A receptor 4	1	11	Small-scale	0.618	High
312046	KCNA3 Potassium voltage-gated channel subfamily A member 3	1	4	High-throughput	0.479	High
312050	GGA2 ADP-ribosylation factor-binding protein GGA2	1	8	Small-scale	0.479	High
312051	VPS35 Vacuolar protein sorting-associated protein 35	1	2	Small-scale	0.479	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025