Protein: NSD2
Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Wolf-Hirschhorn syndrome candidate 1 protein homolog)

Gene: NSD2
Organism: Mus musculus
Interactions: 21
UniProt ID: Q8BVE8

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003149 - membranous septum morphogenesis
GO:0003289 - atrial septum primum morphogenesis
GO:0003290 - atrial septum secundum morphogenesis
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

148718

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.715

High

476234

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

11

Small-scale

0.691

High

1189456

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.691

High

1297456

RAVR1
Ribonucleoprotein PTB-binding 1

1

16

Small-scale

0.691

High

1297453

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

18

Small-scale

0.665

High

1274269

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

19

Small-scale

0.618

High

1297454

EED
Polycomb protein EED

1

20

High-throughput

0.618

High

312602

O88568
Heterogeneous nuclear ribonucleoprotein U

1

19

Small-scale

0.575

High

1297458

BRD4
Bromodomain-containing protein 4

1

20

Small-scale

0.575

High

1283119

NANOG
Homeobox protein NANOG

1

20

Small-scale

0.565

High

688484

TWST1
Twist-related protein 1

1

13

High-throughput

0.561

High

1297451

SALL4
Sal-like protein 4

1

12

Small-scale

0.554

High

1297452

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

17

Small-scale

0.554

High

1297457

SALL1
Sal-like protein 1

1

11

Small-scale

0.554

High

840137

NKX25
Homeobox protein Nkx-2.5

1

20

Small-scale

0.515

High

1225425

SF01
Splicing factor 1

1

6

Small-scale

0.500

High

92667

D3YZC9
Splicing factor 1

1

6

Small-scale

0.479

High

1210202

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.479

High

1242729

Q6P5E3
Sal-like protein 1

1

11

Small-scale

0.479

High

1297455

FOXP3
Forkhead box protein P3

1

13

High-throughput

0.479

High

1223208

HIRA
Protein HIRA

1

20

Small-scale

0.445

High


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Last updated: 11Aug2025