Protein: NOT1
General negative regulator of transcription subunit 1 (Cell division cycle protein 39)

Gene: NOT1, CDC39
Organism: Saccharomyces cerevisiae S288C
Interactions: 116
UniProt ID: P25655

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000749 - response to pheromone triggering conjugation with cellular fusion
GO:0000932 - P-body
GO:0001671 - ATPase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636136

POP2
Poly(A) ribonuclease POP2

16

8

Small-scale

0.988

High

636194

NOT5
General negative regulator of transcription subunit 5

14

4

Small-scale

0.982

High

636165

CAF40
Protein CAF40

14

3

Small-scale

0.982

High

409824

NOT2
General negative regulator of transcription subunit 2

12

6

Small-scale

0.979

High

409955

NOT3
General negative regulator of transcription subunit 3

11

4

Small-scale

0.972

High

636141

DHH1
ATP-dependent RNA helicase DHH1

4

3

Small-scale

0.888

High

636109

NOT1
General negative regulator of transcription subunit 1

2

1

High-throughput

0.811

High

636124

NOT4
General negative regulator of transcription subunit 4

18

1

Small-scale

0.764

High

636113

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

16

8

Small-scale

0.764

High

636162

CF130
Protein CAF130

10

0

Small-scale

0.724

High

636193

RUVB2
RuvB-like protein 2

3

1

High-throughput

0.667

High

636147

NACB2
Nascent polypeptide-associated complex subunit beta-2

3

1

Small-scale

0.661

High

636132

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

1

High-throughput

0.613

High

636192

TFC7
Transcription factor tau 55 kDa subunit

2

0

High-throughput

0.576

High

636153

TAF1
Transcription initiation factor TFIID subunit 1

1

0

Small-scale

0.568

High

636119

SMY2
Protein SMY2

2

0

Small-scale

0.559

High

636130

CAF4
CCR4-associated factor 4

1

3

Small-scale

0.552

High

510438

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.552

High

636127

DEF1
RNA polymerase II degradation factor 1

2

0

High-throughput

0.551

High

636150

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.547

High

629410

PUF4
Pumilio homology domain family member 4

1

4

High-throughput

0.541

High

636123

WHI3
Protein WHI3

1

1

High-throughput

0.541

High

636137

MPT5
Suppressor protein MPT5

1

4

High-throughput

0.541

High

636155

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.541

High

636184

WHI4
Protein WHI4

1

1

High-throughput

0.541

High

539228

YAK1
Dual specificity protein kinase YAK1

1

3

High-throughput

0.536

High

636164

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

636179

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.536

High

636134

SKN7
Transcription factor SKN7

1

0

Small-scale

0.529

High

636122

PIN4
RNA-binding protein PIN4

1

0

High-throughput

0.518

High

636145

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.518

High

636166

NST1
Stress response protein NST1

1

0

High-throughput

0.518

High

636168

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.518

High

636181

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

0

High-throughput

0.518

High

636172

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

Small-scale

0.515

High

636131

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.513

High

636171

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

636185

RBX1
RING-box protein HRT1

1

0

High-throughput

0.513

High

636176

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

Small-scale

0.508

High

636117

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.493

High

636143

NPT1
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.493

High

636156

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

Small-scale

0.493

High

636151

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.489

High

636163

COPA
Coatomer subunit alpha

1

1

High-throughput

0.489

High

636138

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

Small-scale

0.486

High

425455

TFS2
Transcription elongation factor S-II

1

0

Small-scale

0.480

High

636144

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

Small-scale

0.480

High

355370

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

355805

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

356282

H4
Histone H4

1

1

High-throughput

0.479

High

410317

SC160
Protein SCP160

1

1

High-throughput

0.479

High

636114

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

636120

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

Small-scale

0.479

High

636128

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

636129

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.479

High

636148

PRS4
26S proteasome regulatory subunit 4 homolog

1

1

Small-scale

0.479

High

636152

SCD6
Protein SCD6

1

1

Small-scale

0.479

High

636159

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.479

High

636160

CDH1
APC/C activator protein CDH1

1

1

Small-scale

0.479

High

636167

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

636169

H3
Histone H3

1

1

High-throughput

0.479

High

636178

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.479

High

636180

SIZ1
E3 SUMO-protein ligase SIZ1

1

1

High-throughput

0.479

High

636191

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

High-throughput

0.479

High

636195

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

1

Small-scale

0.479

High

334627

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

Small-scale

0.460

High

406830

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

526956

TBP
TATA-box-binding protein

1

0

Small-scale

0.458

High

549789

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

High-throughput

0.458

High

557912

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

621985

SSD1
Protein SSD1

1

0

Small-scale

0.458

High

636110

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

636112

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

636115

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

636125

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

636126

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

636149

TM108
Protein TMA108

1

0

High-throughput

0.458

High

636158

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

636186

SGO1
Shugoshin

1

0

High-throughput

0.458

High

636188

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

636190

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

449935

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

493328

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

627742

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

632978

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

636118

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

636121

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

636133

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

636140

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

636146

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

636183

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.445

High

636182

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

636111

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

365883

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

367790

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

424370

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

555849

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

612202

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

636142

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

636177

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.426

High

636173

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

636154

YJY1
Uncharacterized protein YJR011C

2

0

Small-scale

0.323

High

636135

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.288

High

636116

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.282

High

636189

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.279

Low

636157

ADRO
Probable NADPH:adrenodoxin oxidoreductase, mitochondrial

1

0

High-throughput

0.265

Low

410084

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

Small-scale

0.249

Low

413339

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

480517

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

636170

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

636174

MLP1
Protein MLP1

1

0

Small-scale

0.249

Low

636175

NU100
Nucleoporin NUP100/NSP100

1

0

Small-scale

0.249

Low

636187

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

636139

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

636161

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024