Protein: PEPD
Cytosol non-specific dipeptidase (EC 3.4.13.18) (Aminoacyl-histidine dipeptidase) (Beta-alanyl-histidine dipeptidase) (Carnosinase) (Cysteinylglycinase) (Peptidase D) (Xaa-His dipeptidase) (X-His dipeptidase)

Gene: PEPD
Organism: Escherichia coli K-12
Interactions: 73
UniProt ID: P15288

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
GO:0016805 - dipeptidase activity
GO:0042803 - protein homodimerization activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

582268

PEPD
Cytosol non-specific dipeptidase

1

0

High-throughput

0.663

High

582286

GUAC
GMP reductase

3

0

High-throughput

0.634

High

490445

DEOC
Deoxyribose-phosphate aldolase

2

0

High-throughput

0.585

High

578278

AMPP
Xaa-Pro aminopeptidase

2

0

High-throughput

0.585

High

582272

NTPPA
dTTP/UTP pyrophosphatase

1

1

High-throughput

0.536

High

449936

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.513

High

480546

GRPE
Protein GrpE

1

0

High-throughput

0.513

High

492355

RIBB
3,4-dihydroxy-2-butanone 4-phosphate synthase

1

0

High-throughput

0.513

High

495306

UPP
Uracil phosphoribosyltransferase

1

0

High-throughput

0.513

High

495956

YQGE
UPF0301 protein YqgE

1

0

High-throughput

0.513

High

497188

FER
2Fe-2S ferredoxin

1

0

High-throughput

0.513

High

498092

YCED
Large ribosomal RNA subunit accumulation protein YceD

1

0

High-throughput

0.513

High

498526

DKSA
RNA polymerase-binding transcription factor DksA

1

0

High-throughput

0.513

High

498560

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.513

High

498618

MENB
1,4-dihydroxy-2-naphthoyl-CoA synthase

1

0

High-throughput

0.513

High

499116

DBHB
DNA-binding protein HU-beta

1

0

High-throughput

0.513

High

499501

YEBG
Uncharacterized protein YebG

1

0

High-throughput

0.513

High

499702

ENTB
Enterobactin synthase component B

1

0

High-throughput

0.513

High

500073

MAZE
Antitoxin MazE

1

0

High-throughput

0.513

High

501527

SSB
Single-stranded DNA-binding protein

1

0

High-throughput

0.513

High

582269

PNCB
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.513

High

582273

MSYB
Acidic protein MsyB

1

0

High-throughput

0.513

High

582275

YEIR
Zinc chaperone YeiR

1

0

High-throughput

0.513

High

582278

WBBJ
Putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ

1

0

High-throughput

0.513

High

582281

YBII
Uncharacterized protein YbiI

1

0

High-throughput

0.513

High

582283

TSAC
Threonylcarbamoyl-AMP synthase

1

0

High-throughput

0.513

High

582287

GPMA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

1

0

High-throughput

0.513

High

582289

YDFZ
Putative selenoprotein YdfZ

1

0

High-throughput

0.513

High

582293

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

582306

IDI
Isopentenyl-diphosphate Delta-isomerase

1

0

High-throughput

0.513

High

490484

HSCB
Co-chaperone protein HscB

1

0

High-throughput

0.493

High

495690

FETP

1

0

High-throughput

0.493

High

491129

DNAK
Chaperone protein DnaK

1

0

High-throughput

0.464

High

497150

ACCD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

1

0

High-throughput

0.464

High

358854

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.458

High

582060

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

Small-scale

0.458

High

582294

AMPA
Cytosol aminopeptidase

1

0

High-throughput

0.458

High

469375

YCIH
Uncharacterized protein YciH

1

0

High-throughput

0.279

Low

489153

YIDB
Uncharacterized protein YidB

1

0

High-throughput

0.279

Low

496612

MUG
G/U mismatch-specific DNA glycosylase

1

0

High-throughput

0.279

Low

496698

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.279

Low

498116

YCGL
Protein YcgL

1

0

High-throughput

0.279

Low

498181

ARSC
Arsenate reductase

1

0

High-throughput

0.279

Low

499279

FUCR
L-fucose operon activator

1

0

High-throughput

0.279

Low

499544

YECJ
Uncharacterized protein YecJ

1

0

High-throughput

0.279

Low

500346

FLGM
Negative regulator of flagellin synthesis

1

0

High-throughput

0.279

Low

501760

RELB
Antitoxin RelB

1

0

High-throughput

0.279

Low

582270

HYAE
Hydrogenase-1 operon protein HyaE

1

0

High-throughput

0.279

Low

582271

YCIG
Uncharacterized protein YciG

1

0

High-throughput

0.279

Low

582274

GREB
Transcription elongation factor GreB

1

0

High-throughput

0.279

Low

582276

RIR4
Ribonucleoside-diphosphate reductase 2 subunit beta

1

0

High-throughput

0.279

Low

582277

PMRD
Signal transduction protein PmrD

1

0

High-throughput

0.279

Low

582280

YJEJ
Uncharacterized protein YjeJ

1

0

High-throughput

0.279

Low

582282

FLGN
Flagella synthesis protein FlgN

1

0

High-throughput

0.279

Low

582284

YRHB
Uncharacterized protein YrhB

1

0

High-throughput

0.279

Low

582285

RATB
UPF0125 protein RatB

1

0

High-throughput

0.279

Low

582290

YDIZ
Uncharacterized protein YdiZ

1

0

High-throughput

0.279

Low

582291

PROXY
Multifunctional Ser/Thr-tRNA deacylase ProXp-y

1

0

High-throughput

0.279

Low

582292

SDHE
FAD assembly factor SdhE

1

0

High-throughput

0.279

Low

582295

YMGA
Probable two-component-system connector protein YmgA

1

0

High-throughput

0.279

Low

582296

RACR
DNA-binding transcriptional repressor RacR

1

0

High-throughput

0.279

Low

582298

EUTK
Bacterial microcompartment shell protein EutK

1

0

High-throughput

0.279

Low

582300

MURR
HTH-type transcriptional regulator MurR

1

0

High-throughput

0.279

Low

582301

PRPB
2-methylisocitrate lyase

1

0

High-throughput

0.279

Low

582302

YFCF
Glutathione S-transferase YfcF

1

0

High-throughput

0.279

Low

582303

FLXA
Protein FlxA

1

0

High-throughput

0.279

Low

582304

YFDK
Uncharacterized protein YfdK

1

0

High-throughput

0.279

Low

582305

SSUD
Alkanesulfonate monooxygenase

1

0

High-throughput

0.279

Low

582279

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

582288

YPFJ
Uncharacterized protein YpfJ

1

0

High-throughput

0.249

Low

582297

A2MGH
Putative alpha-2-macroglobulin homolog

1

0

High-throughput

0.232

Low

582299

YFCU
Putative outer membrane usher protein YfcU

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025