Protein: PZP
Pregnancy zone protein (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6)

Gene: PZP
Organism: Homo sapiens
Interactions: 16
UniProt ID: P20742

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004866 - endopeptidase inhibitor activity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

369616

A2MG
Alpha-2-macroglobulin

2

4

High-throughput

0.802

High

634903

DEF6
Defensin-6

2

1

High-throughput

0.628

High

634901

CCL18
C-C motif chemokine 18

1

2

High-throughput

0.536

High

376703

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

6

Small-scale

0.501

High

469660

MMP2
72 kDa type IV collagenase

1

4

Small-scale

0.501

High

634902

TGFB2
Transforming growth factor beta-2 proprotein

1

6

Small-scale

0.501

High

563182

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.489

High

634900

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

529064

TAU
Microtubule-associated protein tau

1

3

Small-scale

0.445

High

360710

COX3
Cytochrome c oxidase subunit 3

1

3

Small-scale

0.437

High

634899

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.437

High

634905

RNF12
E3 ubiquitin-protein ligase RLIM

1

7

High-throughput

0.437

High

634904

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.407

High

634906

TM248
Transmembrane protein 248

1

0

High-throughput

0.279

Low

634907

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.279

Low

634898

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025