Protein: CDK5
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)

Gene: CDK5
Organism: Mus musculus
Interactions: 26
UniProt ID: P49615

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001764 - neuron migration
GO:0001934 - positive regulation of protein phosphorylation
GO:0001963 - synaptic transmission, dopaminergic
GO:0002039 - p53 binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

829600

CD5R1
Cyclin-dependent kinase 5 activator 1

3

7

Small-scale

0.834

High

829604

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

1

High-throughput

0.691

High

509474

CDK1
Cyclin-dependent kinase 1

1

17

Small-scale

0.647

High

546285

NTRK2
BDNF/NT-3 growth factors receptor

1

17

Small-scale

0.646

High

763380

FYN
Tyrosine-protein kinase Fyn

1

14

Small-scale

0.618

High

829605

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

Small-scale

0.618

High

829606

DLG4
Disks large homolog 4

2

2

High-throughput

0.611

High

829609

DLGP1
Disks large-associated protein 1

2

1

High-throughput

0.611

High

829601

DAB1
Disabled homolog 1

2

4

Small-scale

0.602

High

497948

TAU
Microtubule-associated protein tau

2

7

Small-scale

0.595

High

222691

PER2
Period circadian protein homolog 2

1

2

Small-scale

0.578

High

829611

CHIP
E3 ubiquitin-protein ligase CHIP

1

10

Small-scale

0.578

High

515220

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

7

Small-scale

0.575

High

554967

MET
Hepatocyte growth factor receptor

1

11

High-throughput

0.575

High

829610

TSC1
Hamartin

1

18

High-throughput

0.536

High

501122

H10
Histone H1.0

1

8

Small-scale

0.501

High

794639

H11
Histone H1.1

1

20

Small-scale

0.501

High

581220

NFH
Neurofilament heavy polypeptide

1

6

Small-scale

0.479

High

788749

PURA
Transcriptional activator protein Pur-alpha

1

1

Small-scale

0.479

High

829602

TRI72
Tripartite motif-containing protein 72

1

6

Small-scale

0.479

High

829607

WDTC1
WD and tetratricopeptide repeats protein 1

1

8

High-throughput

0.479

High

829608

DPPA3
Developmental pluripotency-associated protein 3

1

1

Small-scale

0.479

High

829612

SEPT5
Septin-5

1

4

Small-scale

0.479

High

102875

G3X9H5
Huntingtin

1

0

High-throughput

0.458

High

829599

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.426

High

829603

ESYT1
Extended synaptotagmin-1

1

1

Small-scale

0.407

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024