Protein: UBA4
Adenylyltransferase and sulfurtransferase UBA4 (Needs CLA4 to survive protein 3) (Ubiquitin-like protein activator 4) [Includes: Adenylyltransferase UBA4 (EC 2.7.7.-); Sulfurtransferase UBA4 (EC 2.8.1.-)]

Gene: UBA4
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P38820

Gene Ontology (top 5):
GO:0001403 - invasive growth in response to glucose limitation
GO:0002098 - tRNA wobble uridine modification
GO:0002143 - tRNA wobble position uridine thiolation
GO:0004792 - thiosulfate sulfurtransferase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755580

URM1
Ubiquitin-related modifier 1

6

2

Small-scale

0.961

High

755573

UBA4
Adenylyltransferase and sulfurtransferase UBA4

5

10

Small-scale

0.915

High

755599

THTR
Thiosulfate sulfurtransferase TUM1

1

0

Small-scale

0.656

High

410225

UBC2
Ubiquitin-conjugating enzyme E2 2

1

19

Small-scale

0.647

High

477271

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

13

High-throughput

0.647

High

565587

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.647

High

600929

UBC1
Ubiquitin-conjugating enzyme E2 1

1

20

Small-scale

0.647

High

703547

UBC6
Ubiquitin-conjugating enzyme E2 6

1

20

Small-scale

0.647

High

493916

HSP72
Heat shock protein SSA2

3

7

High-throughput

0.624

High

701867

SWE1
Mitosis inhibitor protein kinase SWE1

1

4

High-throughput

0.621

High

755589

ATG1
Serine/threonine-protein kinase ATG1

1

2

High-throughput

0.621

High

755574

KOG1
Target of rapamycin complex 1 subunit KOG1

2

1

Small-scale

0.620

High

698346

ELM1
Serine/threonine-protein kinase ELM1

1

0

High-throughput

0.614

High

628030

SIS1
Protein SIS1

2

1

High-throughput

0.584

High

491158

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.571

High

755584

MPS3
Spindle pole body assembly component MPS3

2

0

High-throughput

0.561

High

511244

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.536

High

755588

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

1

Small-scale

0.536

High

755591

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

Small-scale

0.513

High

746807

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

Small-scale

0.501

High

755583

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

691794

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.486

High

748831

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.486

High

755593

MUK1
Protein MUK1

1

0

High-throughput

0.486

High

603309

SNF2
Transcription regulatory protein SNF2

1

1

High-throughput

0.481

High

731103

LHS1
Heat shock protein 70 homolog LHS1

1

8

High-throughput

0.481

High

630677

NFS1
Cysteine desulfurase, mitochondrial

1

0

Small-scale

0.480

High

343600

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

366260

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

368036

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.479

High

543695

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

549731

STI1
Heat shock protein STI1

1

8

High-throughput

0.479

High

662169

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

680689

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

713219

TSA1
Peroxiredoxin TSA1

1

1

High-throughput

0.479

High

741179

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

High-throughput

0.479

High

755582

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

755602

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

8

High-throughput

0.479

High

732484

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

755575

SKN7
Transcription factor SKN7

1

0

High-throughput

0.460

High

755592

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.460

High

755595

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

343386

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

498516

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

686958

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

742784

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

755577

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

755585

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.458

High

755597

SGO1
Shugoshin

1

0

High-throughput

0.458

High

755598

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

755603

HSP42
Heat shock protein 42

1

0

High-throughput

0.458

High

755576

MET30
F-box protein MET30

1

2

High-throughput

0.457

High

556030

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

694659

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

755578

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

745503

KMO
Kynurenine 3-monooxygenase

1

1

High-throughput

0.437

High

755579

ULP2
Ubiquitin-like-specific protease 2

1

2

Small-scale

0.437

High

755600

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.426

High

750082

CUE1
Coupling of ubiquitin conjugation to ER degradation protein 1

1

0

Small-scale

0.287

High

755587

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.265

Low

731947

RT22
Ribosome assembly protein RSM22, mitochondrial

1

0

High-throughput

0.251

Low

747575

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.251

Low

755590

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.251

Low

755594

KAR5
Nuclear fusion protein KAR5

1

0

High-throughput

0.251

Low

660330

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

755581

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

755586

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

755596

GIC2
GTPase-interacting component 2

1

0

Small-scale

0.249

Low

755601

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024