Protein: CAK1
Serine/threonine-protein kinase CAK1 (EC 2.7.11.22) (CDK-activating kinase)

Gene: CAK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 14
UniProt ID: P43568

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364601

CDK1
Cyclin-dependent kinase 1

10

17

Small-scale

0.976

High

438208

CDC37
Hsp90 co-chaperone Cdc37

2

12

Small-scale

0.809

High

835979

SMK1
Sporulation-specific mitogen-activated protein kinase SMK1

2

20

Small-scale

0.781

High

440853

KIN28
Serine/threonine-protein kinase KIN28

2

17

Small-scale

0.778

High

849785

CTK1
CTD kinase subunit alpha

1

17

Small-scale

0.647

High

849784

TWF1
Twinfilin-1

1

3

High-throughput

0.536

High

574806

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

7

High-throughput

0.515

High

586468

PCNA
Proliferating cell nuclear antigen

1

9

High-throughput

0.501

High

746638

DRS1
ATP-dependent RNA helicase DRS1

1

18

High-throughput

0.501

High

849787

VPS54
Vacuolar protein sorting-associated protein 54

1

2

High-throughput

0.464

High

745192

CDC13
Cell division control protein 13

1

1

High-throughput

0.457

High

849786

RNH2B
Ribonuclease H2 subunit B

1

1

High-throughput

0.457

High

545295

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

741811

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High


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Last updated: 11Aug2025