Protein: VPS54
Vacuolar protein sorting-associated protein 54 (CPF1 genetically-interacting protein 1) (Temperature-sensitive clathrin synthetic mutation protein 3)

Gene: VPS54
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: Q12071

Gene Ontology (top 5):
GO:0000938 - GARP complex
GO:0005739 - mitochondrion
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006623 - protein targeting to vacuole

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814910

VPS52
Vacuolar protein sorting-associated protein 52

11

2

Small-scale

0.759

High

864699

VPS53
Vacuolar protein sorting-associated protein 53

8

3

Small-scale

0.751

High

781538

VPS51
Vacuolar protein sorting-associated protein 51

5

0

Small-scale

0.684

High

1061944

TLG2
t-SNARE affecting a late Golgi compartment protein 2

3

1

Small-scale

0.669

High

525472

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.624

High

546662

SSB1
Ribosome-associated molecular chaperone SSB1

3

1

High-throughput

0.624

High

1084222

YPT6
GTP-binding protein YPT6

2

0

Small-scale

0.598

High

1042342

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

1

Small-scale

0.578

High

527962

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.571

High

820067

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

850498

LSB3
LAS seventeen-binding protein 3

1

0

High-throughput

0.518

High

793663

ARL1
ADP-ribosylation factor-like protein 1

1

0

Small-scale

0.513

High

762879

TOR1
Serine/threonine-protein kinase TOR1

1

0

High-throughput

0.493

High

746151

PEP12
Syntaxin PEP12

1

2

Small-scale

0.481

High

849787

CAK1
Serine/threonine-protein kinase CAK1

1

2

High-throughput

0.464

High

432726

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

724277

SNC1
Synaptobrevin homolog 1

1

0

Small-scale

0.458

High

800401

YPT31
GTP-binding protein YPT31/YPT8

1

0

Small-scale

0.458

High

1056518

YSP2
Membrane-anchored lipid-binding protein YSP2

1

0

High-throughput

0.458

High

1084219

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.458

High

1084220

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

742630

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

364799

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.292

High

597298

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.279

Low

722340

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

1084221

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.279

Low

646743

SEC15
Exocyst complex component SEC15

1

0

Small-scale

0.265

Low

796833

EXO84
Exocyst complex component EXO84

1

0

Small-scale

0.265

Low

1054435

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.265

Low

737059

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

844495

GZF3
Protein GZF3

1

0

High-throughput

0.251

Low

849858

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

1055883

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.251

Low

708475

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

795260

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

875338

TBCA
Tubulin-specific chaperone A

1

0

Small-scale

0.249

Low

1045069

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

1062883

RBX1
RING-box protein HRT1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025