Protein: SPO12
Sporulation-specific protein 12

Gene: SPO12
Organism: Saccharomyces cerevisiae S288C
Interactions: 67
UniProt ID: P17123

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0007127 - meiosis I
GO:0030435 - sporulation resulting in formation of a cellular spore
GO:0031536 - positive regulation of exit from mitosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

602117

IMB3
Importin subunit beta-3

2

0

Small-scale

0.618

High

149191

FOB1
DNA replication fork-blocking protein FOB1

2

0

Small-scale

0.593

High

602113

CSM1
Monopolin complex subunit CSM1

2

0

High-throughput

0.570

High

416515

HXKB
Hexokinase-2

1

0

High-throughput

0.513

High

439229

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.513

High

602109

TRX2
Thioredoxin-2

1

0

High-throughput

0.513

High

602110

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.513

High

602114

BMH1
Protein BMH1

1

0

High-throughput

0.513

High

602115

CYS3
Cystathionine gamma-lyase

1

0

High-throughput

0.513

High

602123

FHP
Flavohemoprotein

1

0

High-throughput

0.513

High

602127

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

602128

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.513

High

602130

ADK
Adenosine kinase

1

0

High-throughput

0.513

High

602135

YNN4
Uncharacterized protein YNL134C

1

0

High-throughput

0.513

High

602137

ACT
Actin

1

0

High-throughput

0.513

High

602151

YP11B
Transposon Ty1-PL Gag-Pol polyprotein

1

0

High-throughput

0.513

High

367681

ENO1
Enolase 1

1

1

High-throughput

0.489

High

367883

ENO2
Enolase 2

1

1

High-throughput

0.489

High

454850

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.489

High

455371

RS19B
Small ribosomal subunit protein eS19B

1

1

High-throughput

0.489

High

602129

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

Small-scale

0.486

High

602131

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

Small-scale

0.486

High

602140

MEC3
DNA damage checkpoint control protein MEC3

1

0

Small-scale

0.486

High

602143

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

0

Small-scale

0.486

High

602145

URN1
Pre-mRNA-splicing factor URN1

1

0

Small-scale

0.486

High

602147

PML1
Pre-mRNA leakage protein 1

1

0

Small-scale

0.486

High

602148

USB1
U6 snRNA phosphodiesterase 1

1

0

Small-scale

0.486

High

364315

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

602107

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.460

High

602108

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.460

High

602111

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

0

High-throughput

0.460

High

602112

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.460

High

602118

BRR2
Pre-mRNA-splicing helicase BRR2

1

0

Small-scale

0.460

High

602120

SUMT
Uroporphyrinogen-III C-methyltransferase

1

0

High-throughput

0.460

High

602134

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.460

High

602139

HAP5
Transcriptional activator HAP5

1

0

High-throughput

0.460

High

602144

MTNA
Methylthioribose-1-phosphate isomerase

1

0

Small-scale

0.460

High

602152

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.460

High

602142

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

Small-scale

0.458

High

522972

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

525849

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

368582

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

543728

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

575884

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

602149

PMG3
Phosphoglycerate mutase 3

1

1

High-throughput

0.407

High

365551

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.279

Low

368318

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

0

High-throughput

0.279

Low

518191

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.279

Low

554999

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.279

Low

602105

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.279

Low

602116

EF2
Elongation factor 2

1

0

High-throughput

0.279

Low

602121

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.279

Low

602132

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.279

Low

602133

AZR1
Azole resistance protein 1

1

0

High-throughput

0.279

Low

602136

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.279

Low

602150

HSP42
Heat shock protein 42

1

0

High-throughput

0.279

Low

602106

UPP
Uracil phosphoribosyltransferase

1

0

Small-scale

0.265

Low

602122

OSH3
Oxysterol-binding protein homolog 3

1

0

Small-scale

0.265

Low

602125

FIR1
Factor interacting with REF2

1

0

Small-scale

0.265

Low

602119

NIP80
Protein NIP100

1

0

High-throughput

0.251

Low

602126

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

0

High-throughput

0.251

Low

602141

YM46
Uncharacterized protein YMR181C

1

0

High-throughput

0.251

Low

602138

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

602146

CENPO
Inner kinetochore subunit MCM21

1

0

High-throughput

0.238

Low

510159

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

578788

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

602124

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025