Protein: GSH1
Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-ECS) (GCS) (Gamma-glutamylcysteine synthetase)

Gene: GSH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 25
UniProt ID: P32477

Gene Ontology (top 5):
GO:0004357 - glutamate-cysteine ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006750 - glutathione biosynthetic process
GO:0042542 - response to hydrogen peroxide

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

737598

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.536

High

737603

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.536

High

364978

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.513

High

394351

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.513

High

737605

NEW1
[NU+] prion formation protein 1

1

0

High-throughput

0.513

High

509453

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

579041

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

392417

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

523365

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526179

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544171

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

737596

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

737599

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

486090

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

592096

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

675813

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

726844

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

737597

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.426

High

737600

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

737604

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

737601

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

706505

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

737602

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

737606

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

575411

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025