Protein: ORC5
Origin recognition complex subunit 5 (Origin recognition complex 53 kDa subunit)

Gene: ORC5
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P50874

Gene Ontology (top 5):
GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

698724

ORC2
Origin recognition complex subunit 2

13

4

Small-scale

0.981

High

842058

ORC4
Origin recognition complex subunit 4

11

13

Small-scale

0.980

High

842056

ORC1
Origin recognition complex subunit 1

13

13

Small-scale

0.978

High

447803

CDC6
Cell division control protein 6

6

14

Small-scale

0.937

High

842057

ORC3
Origin recognition complex subunit 3

8

0

Small-scale

0.916

High

755746

ORC6
Origin recognition complex subunit 6

7

0

Small-scale

0.915

High

667602

MCM2
DNA replication licensing factor MCM2

4

5

Small-scale

0.901

High

842054

ORC5
Origin recognition complex subunit 5

3

2

Small-scale

0.849

High

744584

PCH2
Pachytene checkpoint protein 2

1

0

Small-scale

0.687

High

811830

CDT1
Cell division cycle protein CDT1

3

0

Small-scale

0.633

High

842064

HAT1
Histone acetyltransferase type B catalytic subunit

3

0

Small-scale

0.622

High

667870

MCM5
Minichromosome maintenance protein 5

1

6

Small-scale

0.618

High

754015

RRM3
ATP-dependent DNA helicase RRM3

2

0

Small-scale

0.609

High

355944

H2B2
Histone H2B.2

2

2

High-throughput

0.601

High

842065

RLF2
Chromatin assembly factor 1 subunit p90

2

0

Small-scale

0.583

High

765949

HAT2
Histone acetyltransferase type B subunit 2

2

0

Small-scale

0.576

High

842055

MCM6
DNA replication licensing factor MCM6

1

6

Small-scale

0.575

High

355549

H2B1
Histone H2B.1

2

2

High-throughput

0.571

High

491818

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.571

High

842061

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.565

High

805180

SUM1
Suppressor of mar1-1 protein

2

0

Small-scale

0.559

High

768918

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

705419

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.546

High

687543

DBF4
DDK kinase regulatory subunit DBF4

1

0

Small-scale

0.529

High

811002

CUL8
Cullin-8

1

0

Small-scale

0.525

High

457044

SWI6
Regulatory protein SWI6

1

0

Small-scale

0.518

High

620018

MPIP
M-phase inducer phosphatase

1

0

Small-scale

0.518

High

376853

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.513

High

688654

MCM10
Minichromosome maintenance protein 10

1

1

Small-scale

0.501

High

693723

IME2
Meiosis induction protein kinase IME2/SME1

1

0

Small-scale

0.480

High

356596

H4
Histone H4

1

1

High-throughput

0.479

High

842059

H3
Histone H3

1

3

High-throughput

0.479

High

842063

NOC3
Nucleolar complex-associated protein 3

1

0

Small-scale

0.460

High

392503

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

599979

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

0

High-throughput

0.458

High

662756

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

673209

CGS5
S-phase entry cyclin-5

1

0

Small-scale

0.458

High

774185

FKH1
Fork head protein homolog 1

1

0

Small-scale

0.458

High

494432

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

511983

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

695087

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

731124

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.445

High

633383

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

733269

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

792386

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

745766

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

842062

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

746059

YBH1
Uncharacterized protein YBL071C

1

0

High-throughput

0.238

Low

772568

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low

842060

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024