HitPredict

Interactor 1: GLRX4 (P32642)
Monothiol glutaredoxin-4
Gene: GRX4

Interactor 2: BOL1 (Q3E793)
BolA-like protein 1
Gene: BOL1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	18719252
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BolA~Glutaredoxin
Common GO terms	GO:0006879 - intracellular iron ion homeostasis GO:0016226 - iron-sulfur cluster assembly GO:1990229 - iron-sulfur cluster assembly complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Sc			1 110
+	Sc
		1044196 GLRX3_YEAST (1-244): 3.2e-70: 217: 66.67		BOL1_YEAST (1-110): 6e-41: 132: 100.00
+	Sc
		916994 GLRX3_YEAST (1-244): 3.2e-70: 217: 66.67		BOL2_YEAST (2-105): 1.82e-20: 81.1: 21.91
+	Hs
		300257 GLRX3_HUMAN (8-235): 2.67e-56: 184: 38.60		BOLA1_HUMAN (3-110): 9.46e-33: 113: 31.48
+	Sc
		744226 GLRX4_YEAST (1-244): 2.21e-69: 215: 100.00		BOL2_YEAST (2-105): 1.82e-20: 81.1: 21.91
+	Sp
		268108 GLRX4_SCHPO (1-234): 3.96e-57: 183: 41.00		UVI31_SCHPO (1-104): 1.93e-27: 98.5: 44.34
+	Sc
		813884 GLRX3_YEAST (1-244): 3.2e-70: 217: 66.67		BOL3_YEAST (8-100): 2.73e-12: 60.3: 23.66
+	Sc
		744224 GLRX4_YEAST (1-244): 2.21e-69: 215: 100.00		BOL3_YEAST (8-100): 2.73e-12: 60.3: 23.66
+	Hs
		300237 GLRX3_HUMAN (8-235): 2.67e-56: 184: 38.60		BOLA2_HUMAN (25-110): 1.14e-24: 90.8: 26.14
+	Sp
		153749 GLRX4_SCHPO (1-234): 3.96e-57: 183: 41.00		YETB_SCHPO (27-107): 3.01e-22: 84.6: 22.22
+	At
		1228146 GRS16_ARATH (93-234): 1.35e-39: 140: 30.00		BOLA1_ARATH (2-108): 2.34e-33: 115: 36.45
+	At
		1285025 GRS16_ARATH (93-234): 1.35e-39: 140: 30.00		SUFE1_ARATH (8-104): 1.59e-30: 113: 37.37
+	At
		1228144 GRS14_ARATH (144-234): 4.92e-39: 135: 48.35		BOLA1_ARATH (2-108): 2.34e-33: 115: 36.45
+	At
		1228147 GRS15_ARATH (118-234): 2.31e-38: 133: 32.48		BOLA1_ARATH (2-108): 2.34e-33: 115: 36.45
+	At
		1285023 GRS14_ARATH (144-234): 4.92e-39: 135: 48.35		SUFE1_ARATH (8-104): 1.59e-30: 113: 37.37
+	Dm
		55144 Q9VJZ6_DROME (1-235): 2.17e-49: 163: 35.32		A1Z933_DROME (21-106): 1.13e-21: 83.1: 26.74
+	At
		1285026 GRS15_ARATH (118-234): 2.31e-38: 133: 32.48		SUFE1_ARATH (8-104): 1.59e-30: 113: 37.37
+	Hs
		300156 GLRX3_HUMAN (8-235): 2.67e-56: 184: 38.60		BOLA3_HUMAN (4-104): 8.34e-10: 53.4: 18.81
+	At
		1300995 GRS16_ARATH (93-234): 1.35e-39: 140: 30.00		BOLA2_ARATH (17-110): 2.76e-21: 82.3: 27.08
+	Dm
		55137 Q8SXQ5_DROME (122-234): 4.01e-40: 137: 35.40		A1Z933_DROME (21-106): 1.13e-21: 83.1: 26.74
+	At
		1285240 GRS14_ARATH (144-234): 4.92e-39: 135: 48.35		BOLA2_ARATH (17-110): 2.76e-21: 82.3: 27.08