Protein: HST1
NAD-dependent protein deacetylase HST1 (EC 2.3.1.286) (Homologous to SIR2 protein 1) (Regulatory protein SIR2 homolog 1)

Gene: HST1
Organism: Saccharomyces cerevisiae S288C
Interactions: 25
UniProt ID: P53685

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005637 - nuclear inner membrane
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805183

SUM1
Suppressor of mar1-1 protein

6

1

Small-scale

0.729

High

864124

RFM1
Repression factor of MSEs protein 1

5

1

Small-scale

0.709

High

733280

SET3
SET domain-containing protein 3

5

11

Small-scale

0.706

High

747248

SIF2
SIR4-interacting protein SIF2

4

4

Small-scale

0.687

High

774400

HOS4
Protein HOS4

4

9

Small-scale

0.687

High

516897

SIR4
Regulatory protein SIR4

1

1

Small-scale

0.618

High

630089

SNT1
Probable DNA-binding protein SNT1

2

8

Small-scale

0.612

High

859057

HOS2
Probable histone deacetylase HOS2

1

8

Small-scale

0.515

High

606091

RAD53
Serine/threonine-protein kinase RAD53

1

2

Small-scale

0.501

High

540615

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

Small-scale

0.493

High

759414

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

698892

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

716307

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

755788

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

10

Small-scale

0.479

High

858493

SAP4
SIT4-associating protein SAP4

1

3

High-throughput

0.479

High

864121

SIZ1
E3 SUMO-protein ligase SIZ1

1

2

High-throughput

0.479

High

864123

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

743907

AKL1
Serine/threonine-protein kinase AKL1

1

5

High-throughput

0.470

High

864122

TOS4
Protein TOS4

1

0

Small-scale

0.458

High

355572

H2B1
Histone H2B.1

1

9

High-throughput

0.445

High

491991

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

512196

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

568127

TPM1
Tropomyosin-1

1

0

High-throughput

0.269

Low

864125

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.249

Low

864120

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024