Protein: HOLA
DNA polymerase III subunit delta (EC 2.7.7.7)

Gene: HOLA
Organism: Escherichia coli K-12
Interactions: 53
UniProt ID: P28630

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0003887 - DNA-directed DNA polymerase activity
GO:0006260 - DNA replication
GO:0006261 - DNA-templated DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704147

HOLB
DNA polymerase III subunit delta'

9

1

Small-scale

0.979

High

445422

DPO3X
DNA polymerase III subunit tau

8

0

Small-scale

0.919

High

496364

DPO3B
Beta sliding clamp

4

0

Small-scale

0.866

High

522205

DPO3A
DNA polymerase III subunit alpha

3

0

Small-scale

0.646

High

395123

DPO3E
DNA polymerase III subunit epsilon

3

0

High-throughput

0.641

High

704148

HOLD
DNA polymerase III subunit psi

3

0

Small-scale

0.634

High

704146

HOLA
DNA polymerase III subunit delta

1

0

Small-scale

0.614

High

704149

HOLC
DNA polymerase III subunit chi

2

0

Small-scale

0.607

High

657347

MUTL
DNA mismatch repair protein MutL

1

0

Small-scale

0.537

High

497864

FDNH
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit

2

1

High-throughput

0.537

High

495339

UVRB
UvrABC system protein B

1

0

High-throughput

0.518

High

499303

GLCC
Glc operon transcriptional activator

1

0

High-throughput

0.518

High

704163

ARIR
Probable two-component-system connector protein AriR

1

0

High-throughput

0.518

High

704167

DINJ
Antitoxin DinJ

1

0

High-throughput

0.518

High

704157

YSAA
Putative electron transport protein YsaA

1

1

High-throughput

0.494

High

491166

DNAK
Chaperone protein DnaK

1

0

High-throughput

0.464

High

498562

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

704168

YKGN
Putative transposase YkgN

1

0

High-throughput

0.438

High

704153

YEHB
Outer membrane usher protein YehB

2

0

High-throughput

0.318

High

602028

NFSA
Oxygen-insensitive NADPH nitroreductase

1

0

High-throughput

0.308

High

498287

BCCP
Biotin carboxyl carrier protein of acetyl-CoA carboxylase

2

0

High-throughput

0.307

High

500899

PPX
Exopolyphosphatase

2

0

High-throughput

0.307

High

704161

MACA
Macrolide export protein MacA

1

0

High-throughput

0.292

High

704164

YDCK
Uncharacterized acetyltransferase YdcK

1

0

High-throughput

0.292

High

500685

NUOE
NADH-quinone oxidoreductase subunit E

1

0

High-throughput

0.282

High

500975

YIIF
Uncharacterized protein YiiF

1

0

High-throughput

0.282

High

501594

TRMH
tRNA

1

0

High-throughput

0.282

High

613285

MINC
Septum site-determining protein MinC

1

0

High-throughput

0.282

High

704151

ALSK
D-allose kinase

1

0

High-throughput

0.282

High

704155

USPC
Universal stress protein C

1

0

High-throughput

0.282

High

704156

YFHL
Ferredoxin YfhL

1

0

High-throughput

0.282

High

704160

FIXX
Ferredoxin-like protein FixX

1

0

High-throughput

0.282

High

704162

GFCC
Uncharacterized protein GfcC

1

0

High-throughput

0.282

High

704166

YQJH
NADPH-dependent ferric-chelate reductase

1

0

High-throughput

0.282

High

480549

GRPE
Protein GrpE

1

0

High-throughput

0.279

Low

664127

ACCC
Biotin carboxylase

1

0

High-throughput

0.279

Low

704152

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.279

Low

704154

PEPB
Peptidase B

1

0

High-throughput

0.279

Low

489736

CH60
Chaperonin GroEL

1

0

High-throughput

0.269

Low

704159

YEEW
Protein YeeW

1

0

High-throughput

0.264

Low

491448

IF2
Translation initiation factor IF-2

1

0

High-throughput

0.253

Low

492532

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.253

Low

493104

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.253

Low

493947

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.253

Low

499898

RL16
Large ribosomal subunit protein uL16

1

0

High-throughput

0.253

Low

704158

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.253

Low

491972

NUSB
Transcription antitermination protein NusB

1

0

High-throughput

0.249

Low

495094

TRMD
tRNA

1

0

High-throughput

0.249

Low

483831

DICB
Division inhibition protein DicB

1

0

High-throughput

0.238

Low

704150

METN
Methionine import ATP-binding protein MetN

1

0

High-throughput

0.238

Low

704165

FLXA
Protein FlxA

1

0

High-throughput

0.238

Low

704169

YMDE
Putative uncharacterized protein YmdE

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025