Protein: BEM2
GTPase-activating protein BEM2/IPL2 (Bud emergence protein 2)

Gene: BEM2
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: P39960

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0003729 - mRNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005628 - prospore membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

649961

BUD14
Bud site selection protein 14

5

1

Small-scale

0.923

High

580318

CDC42
Cell division control protein 42

2

20

Small-scale

0.767

High

743145

BOB1
Protein BOB1

1

1

High-throughput

0.698

High

758772

SAK1
SNF1-activating kinase 1

1

1

High-throughput

0.691

High

765674

DUF1
DUB-associated factor 1

1

6

High-throughput

0.691

High

765628

RIO2
Serine/threonine-protein kinase RIO2

3

3

High-throughput

0.671

High

693116

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

5

Small-scale

0.647

High

765632

PRK1
Actin-regulating kinase PRK1

1

6

Small-scale

0.647

High

366338

HSP82
ATP-dependent molecular chaperone HSP82

3

11

High-throughput

0.633

High

491316

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.633

High

594326

PP11
Serine/threonine-protein phosphatase PP1-1

2

6

High-throughput

0.621

High

419749

RHO2
GTP-binding protein RHO2

1

20

Small-scale

0.621

High

765652

RHO4
GTP-binding protein RHO4

1

20

Small-scale

0.621

High

584741

CSK22
Casein kinase II subunit alpha'

1

17

High-throughput

0.618

High

744622

TAF5
Transcription initiation factor TFIID subunit 5

1

13

High-throughput

0.618

High

760570

SSN3
Meiotic mRNA stability protein kinase SSN3

1

7

High-throughput

0.618

High

765668

RTK1
Probable serine/threonine-protein kinase RTK1

1

5

High-throughput

0.618

High

765643

CDH1
APC/C activator protein CDH1

1

8

Small-scale

0.618

High

765673

ARP7
Actin-related protein 7

1

18

High-throughput

0.595

High

592909

SRP54
Signal recognition particle subunit SRP54

2

0

High-throughput

0.595

High

707273

RT05
Small ribosomal subunit protein uS5m

2

0

High-throughput

0.595

High

543789

HSC82
ATP-dependent molecular chaperone HSC82

2

11

High-throughput

0.571

High

743345

RM16
Large ribosomal subunit protein uL16m

2

0

High-throughput

0.563

High

494041

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

511416

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

765627

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

765636

NOP2
25S rRNA

2

2

High-throughput

0.537

High

399483

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

676076

XPO1
Exportin-1

1

14

High-throughput

0.536

High

754436

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.536

High

756249

KEL1
Kelch repeat-containing protein 1

1

8

High-throughput

0.536

High

765631

SDP1
Dual-specificity protein phosphatase SDP1

1

1

High-throughput

0.536

High

765638

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

765644

TWF1
Twinfilin-1

1

4

High-throughput

0.536

High

765647

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

765656

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

613058

SPA2
Protein SPA2

1

2

High-throughput

0.515

High

697881

ALK2
Serine/threonine-protein kinase Haspin homolog ALK2

1

0

High-throughput

0.513

High

751365

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.513

High

765670

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

765654

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.493

High

765659

GCN5
Histone acetyltransferase GCN5

1

9

High-throughput

0.489

High

410390

SC160
Protein SCP160

1

6

High-throughput

0.479

High

478228

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

675741

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.479

High

680730

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

696332

PP12
Serine/threonine-protein phosphatase PP1-2

1

3

High-throughput

0.479

High

765630

TM108
Protein TMA108

1

1

High-throughput

0.479

High

765640

MTNB
Methylthioribulose-1-phosphate dehydratase

1

1

High-throughput

0.479

High

765649

NOP15
Ribosome biogenesis protein 15

1

5

High-throughput

0.479

High

765653

NUM1
Nuclear migration protein NUM1

1

17

High-throughput

0.479

High

765660

YD239
Uncharacterized protein YDR239C

1

1

High-throughput

0.479

High

765661

GIS1
Transcriptional activator/repressor GIS1

1

11

High-throughput

0.479

High

765665

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.479

High

765669

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

410130

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.470

High

645041

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

700914

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

746899

YBS1
Uncharacterized protein YBR071W

1

0

High-throughput

0.458

High

765646

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

765662

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

765666

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

765667

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

368090

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

485526

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.445

High

540584

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

556074

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

633246

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

694756

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

757168

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

4

High-throughput

0.445

High

765641

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.445

High

765648

PFD4
Prefoldin subunit 4

1

2

High-throughput

0.445

High

765650

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.445

High

765664

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

6

High-throughput

0.445

High

765672

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

356491

H4
Histone H4

1

4

High-throughput

0.437

High

416227

SIR2
NAD-dependent histone deacetylase SIR2

1

2

High-throughput

0.437

High

662304

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

765633

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.437

High

765651

H3
Histone H3

1

9

High-throughput

0.437

High

765663

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

765671

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.437

High

690620

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

392439

H2A2
Histone H2A.2

1

4

High-throughput

0.407

High

765657

ADA2
Transcriptional adapter 2

1

4

High-throughput

0.407

High

765635

SA185
SIT4-associating protein SAP185

2

0

High-throughput

0.328

High

765629

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

2

0

High-throughput

0.324

High

765655

MCE1
mRNA-capping enzyme subunit alpha

2

0

High-throughput

0.307

High

765658

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.298

High

752037

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.279

Low

765637

KRI1
Protein KRI1

1

0

High-throughput

0.279

Low

765645

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.279

Low

692791

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.269

Low

558069

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

649272

CBPS
Carboxypeptidase S

1

0

High-throughput

0.249

Low

716247

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

716433

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

757983

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

762222

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

765634

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

765639

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

765642

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

425969

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.232

Low

754123

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.232

Low

757420

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024