Protein: PMA1
Plasma membrane ATPase 1 (EC 7.1.2.1) (Proton pump 1)

Gene: PMA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 159
UniProt ID: P05030

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008553 - P-type proton-exporting transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420855

PMA1
Plasma membrane ATPase 1

5

13

Small-scale

0.902

High

420870

HSP71
Heat shock protein SSA1

5

4

High-throughput

0.695

High

420873

ATC1
Calcium-transporting ATPase 1

1

15

High-throughput

0.665

High

391961

HSP82
ATP-dependent molecular chaperone HSP82

3

4

High-throughput

0.640

High

420952

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

3

High-throughput

0.640

High

420905

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

2

3

High-throughput

0.614

High

420858

RS3
Small ribosomal subunit protein uS3

2

2

Small-scale

0.584

High

420880

GAS1
1,3-beta-glucanosyltransferase GAS1

2

2

Small-scale

0.584

High

420902

PMP1
Plasma membrane ATPase proteolipid 1

2

1

Small-scale

0.584

High

420925

PHO88
SRP-independent targeting protein 3

2

1

High-throughput

0.584

High

420965

PIL1
Sphingolipid long chain base-responsive protein PIL1

2

0

High-throughput

0.559

High

420874

KSS1
Mitogen-activated protein kinase KSS1

1

6

High-throughput

0.536

High

420969

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

420975

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

6

High-throughput

0.536

High

420976

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

420946

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

420885

SIS1
Protein SIS1

1

1

High-throughput

0.515

High

420883

KC11
Casein kinase I homolog 1

1

6

Small-scale

0.501

High

420957

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

4

Small-scale

0.501

High

420875

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.500

High

420898

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.500

High

420921

IMB2
Importin subunit beta-2

1

3

High-throughput

0.500

High

420994

RTC1
Restriction of telomere capping protein 1

1

2

High-throughput

0.500

High

420984

NHX1
Endosomal/prevacuolar sodium/hydrogen exchanger

1

1

High-throughput

0.494

High

420913

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

8

High-throughput

0.489

High

420879

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.479

High

420897

ARP2
Actin-related protein 2

1

0

High-throughput

0.479

High

420939

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.479

High

364213

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

416974

VDAC1
Non-selective voltage-gated ion channel 1

1

3

Small-scale

0.479

High

420856

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

2

Small-scale

0.479

High

420866

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.479

High

420871

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.479

High

420878

GAP1
General amino-acid permease GAP1

1

3

Small-scale

0.479

High

420890

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

420892

COQ8
Atypical kinase COQ8, mitochondrial

1

3

High-throughput

0.479

High

420895

BMH1
Protein BMH1

1

13

High-throughput

0.479

High

420896

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

420900

SNQ2
Protein SNQ2

1

4

High-throughput

0.479

High

420904

PRS6A
26S proteasome regulatory subunit 6A

1

8

High-throughput

0.479

High

420912

MID2
Cell wall integrity sensor MID2

1

2

Small-scale

0.479

High

420915

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

420916

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

420917

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

3

High-throughput

0.479

High

420919

ATG8
Autophagy-related protein 8

1

3

High-throughput

0.479

High

420920

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

1

High-throughput

0.479

High

420931

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

420934

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

420938

SSO2
Protein SSO2

1

4

High-throughput

0.479

High

420943

MLP2
Protein MLP2

1

2

High-throughput

0.479

High

420944

QDR2
Quinidine resistance protein 2

1

3

High-throughput

0.479

High

420949

PMP2
Plasma membrane ATPase proteolipid 2

1

1

High-throughput

0.479

High

420950

MID1
Stretch-activated cation channel MID1

1

1

Small-scale

0.479

High

420956

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

420961

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

420967

YG3A
Uncharacterized protein YGR130C

1

4

Small-scale

0.479

High

420973

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

420980

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

2

High-throughput

0.479

High

420983

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.479

High

420985

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

420988

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

421001

DBP10
ATP-dependent RNA helicase DBP10

1

3

High-throughput

0.479

High

421002

RUVB2
RuvB-like protein 2

1

4

High-throughput

0.479

High

421004

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

2

High-throughput

0.479

High

421005

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.479

High

421006

TECR
Very-long-chain enoyl-CoA reductase

1

1

High-throughput

0.479

High

420909

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

1

High-throughput

0.470

High

420926

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.470

High

420927

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

1

High-throughput

0.470

High

420936

ERP2
Protein ERP2

1

4

High-throughput

0.470

High

420954

SPC1
Signal peptidase complex subunit 1

1

2

High-throughput

0.470

High

383393

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

420857

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

420859

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

420860

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

420862

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

420863

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

420864

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

420867

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

420868

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

420881

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

420882

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

420888

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

420903

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

420908

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

420910

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

420922

ECM33
Cell wall protein ECM33

1

0

High-throughput

0.458

High

420923

IST2
Increased sodium tolerance protein 2

1

0

High-throughput

0.458

High

420924

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

420935

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

420941

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

420951

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

420955

TOH1
Probable circularly permuted 1,3-beta-glucanase YJL171C

1

0

High-throughput

0.458

High

420959

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

420960

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.458

High

420974

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

420977

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

420986

SEG1
Eisosome protein SEG1

1

0

Small-scale

0.458

High

420987

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

420990

YL413
Cell membrane protein YLR413W

1

0

High-throughput

0.458

High

420992

LAM6
Membrane-anchored lipid-binding protein LAM6

1

0

High-throughput

0.458

High

420999

MRH1
Protein MRH1

1

0

High-throughput

0.458

High

420869

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.457

High

420865

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

18

High-throughput

0.445

High

420872

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

420901

PEP12
Syntaxin PEP12

1

3

Small-scale

0.445

High

420933

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.445

High

420942

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

420962

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

1

Small-scale

0.439

High

420861

CDC31
Cell division control protein 31

1

7

Small-scale

0.437

High

420876

BGL2
Glucan 1,3-beta-glucosidase

1

1

Small-scale

0.437

High

420877

PDI
Protein disulfide-isomerase

1

1

High-throughput

0.437

High

420884

VPS3
Vacuolar protein sorting-associated protein 3

1

1

Small-scale

0.437

High

420891

AP2B
AP-2 complex subunit beta

1

3

Small-scale

0.437

High

420894

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

420907

IXR1
Intrastrand cross-link recognition protein

1

4

Small-scale

0.437

High

420914

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

1

High-throughput

0.437

High

420928

ECM29
Proteasome component ECM29

1

5

High-throughput

0.437

High

420929

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.437

High

420930

SFB3
SED5-binding protein 3

1

3

Small-scale

0.437

High

420945

SEC24
Protein transport protein SEC24

1

3

Small-scale

0.437

High

420947

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

420958

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

420963

VID30
GID complex subunit 1

1

1

High-throughput

0.437

High

420964

ERV14
ER-derived vesicles protein ERV14

1

4

High-throughput

0.437

High

420968

ERV29
ER-derived vesicles protein ERV29

1

1

High-throughput

0.437

High

420972

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.437

High

420978

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.437

High

420979

VPS60
Vacuolar protein-sorting-associated protein 60

1

3

Small-scale

0.437

High

420993

GAS5
1,3-beta-glucanosyltransferase GAS5

1

2

High-throughput

0.437

High

420996

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

421003

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.437

High

420918

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

420886

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

420989

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.279

Low

420997

UPPS
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.279

Low

420998

DAP1
Damage response protein 1

1

0

High-throughput

0.279

Low

420906

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.261

Low

420887

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.249

Low

420889

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

420893

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

420899

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

420911

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

420932

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

420940

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

High-throughput

0.249

Low

420948

SAS2
Histone acetyltransferase SAS2

1

0

Small-scale

0.249

Low

420953

STU2
Protein STU2

1

0

High-throughput

0.249

Low

420966

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

420971

PGA2
Processing of GAS1 and ALP protein 2

1

0

High-throughput

0.249

Low

420981

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

420982

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low

420991

EXP1
ER export of PMA1 protein 1

1

0

High-throughput

0.249

Low

420995

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

421000

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.249

Low

421007

DET1
Broad-range acid phosphatase DET1

1

0

High-throughput

0.249

Low

421008

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

420937

NPR2
Nitrogen permease regulator 2

1

0

High-throughput

0.232

Low

420970

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025