Protein: TFB1
General transcription and DNA repair factor IIH subunit TFB1 (TFIIH subunit TFB1) (RNA polymerase II transcription factor B 73 kDa subunit) (RNA polymerase II transcription factor B p73 subunit) (RNA polymerase II transcription factor B subunit 1)

Gene: TFB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: P32776

Gene Ontology (top 5):
GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005675 - transcription factor TFIIH holo complex
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744626

SSL1
General transcription and DNA repair factor IIH subunit SSL1

10

2

Small-scale

0.975

High

449325

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

12

2

Small-scale

0.972

High

744618

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

3

2

Small-scale

0.805

High

744630

TFB4
General transcription and DNA repair factor IIH subunit TFB4

10

1

Small-scale

0.757

High

744624

TFB3
RNA polymerase II transcription factor B subunit 3

6

2

Small-scale

0.732

High

454654

RAD2
DNA repair protein RAD2

5

2

Small-scale

0.719

High

744603

T2EA
Transcription initiation factor IIE subunit alpha

5

2

Small-scale

0.715

High

744622

TFB2
General transcription and DNA repair factor IIH subunit TFB2

4

2

Small-scale

0.666

High

744607

CCL1
Cyclin CCL1

3

1

Small-scale

0.643

High

594274

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

1

Small-scale

0.633

High

440832

KIN28
Serine/threonine-protein kinase KIN28

3

2

Small-scale

0.624

High

575244

RAD4
DNA repair protein RAD4

2

3

Small-scale

0.595

High

744597

ATG19
Autophagy-related protein 19

2

0

High-throughput

0.594

High

744617

COG2
Conserved oligomeric Golgi complex subunit 2

2

0

High-throughput

0.594

High

744596

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

Small-scale

0.586

High

744634

TFB5
General transcription and DNA repair factor IIH subunit TFB5

2

0

Small-scale

0.585

High

744620

MEC3
DNA damage checkpoint control protein MEC3

2

0

High-throughput

0.582

High

576954

AMPL
Vacuolar aminopeptidase 1

2

1

High-throughput

0.566

High

628051

FKBP
FK506-binding protein 1

2

0

High-throughput

0.563

High

703892

RAD14
DNA repair protein RAD14

1

1

Small-scale

0.561

High

743963

RAD23
UV excision repair protein RAD23

1

2

Small-scale

0.561

High

744604

T2EB
Transcription initiation factor IIE subunit beta

2

0

Small-scale

0.547

High

544245

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

547862

NHP6B
Non-histone chromosomal protein 6B

1

2

Small-scale

0.527

High

744625

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.518

High

744627

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.518

High

744599

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.513

High

744628

RAD34
DNA repair protein RAD34

1

3

Small-scale

0.501

High

636948

CCA1
CCA tRNA nucleotidyltransferase, mitochondrial

1

0

High-throughput

0.493

High

744623

ESP1
Separin

1

0

High-throughput

0.493

High

744608

CDC27
Anaphase-promoting complex subunit CDC27

1

1

High-throughput

0.489

High

547778

NHP6A
Non-histone chromosomal protein 6A

1

2

Small-scale

0.481

High

744601

ELF1
Transcription elongation factor 1

1

0

Small-scale

0.480

High

624883

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.460

High

560233

TOP3
DNA topoisomerase 3

1

0

High-throughput

0.458

High

579076

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

632789

DBP5
ATP-dependent RNA helicase DBP5

1

0

Small-scale

0.458

High

706580

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

744598

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

744610

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

744613

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.458

High

744632

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

744600

VPS21
Vacuolar protein sorting-associated protein 21

1

0

High-throughput

0.438

High

744611

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.438

High

744612

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.438

High

744619

PTA1
Pre-tRNA-processing protein PTA1

1

0

High-throughput

0.438

High

744621

RMI1
RecQ-mediated genome instability protein 1

1

0

High-throughput

0.438

High

744629

MCA1
Metacaspase-1

1

0

High-throughput

0.438

High

381033

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

744633

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

744609

DNPEP
Aspartyl aminopeptidase 4

1

1

High-throughput

0.417

High

640699

RT28
Small ribosomal subunit protein uS15m

2

0

High-throughput

0.324

High

744605

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.282

High

744614

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.279

Low

577368

MTF1
Mitochondrial transcription factor 1

1

0

High-throughput

0.269

Low

368150

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.238

Low

569391

DPM1
Dolichol-phosphate mannosyltransferase

1

0

High-throughput

0.238

Low

575415

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.238

Low

704124

TRK2
Low-affinity potassium transport protein

1

0

High-throughput

0.238

Low

744602

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.238

Low

744606

APE3
Aminopeptidase Y

1

0

High-throughput

0.238

Low

744615

YIP4
Protein YIP4

1

0

High-throughput

0.238

Low

744616

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

1

0

High-throughput

0.238

Low

744631

DAP1
Damage response protein 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025