Protein: IF4A1
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)

Gene: IF4A1, Eif4a1
Organism: Mus musculus
Interactions: 23
UniProt ID: P60843

Gene Ontology (top 5):
GO:0002183 - cytoplasmic translational initiation
GO:0003724 - RNA helicase activity
GO:0003725 - double-stranded RNA binding
GO:0003743 - translation initiation factor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

954049

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

2

20

Small-scale

0.789

High

954046

PDCD4
Programmed cell death protein 4

1

15

Small-scale

0.716

High

954052

WDTC1
WD and tetratricopeptide repeats protein 1

1

10

High-throughput

0.618

High

954056

EED
Polycomb protein EED

1

19

High-throughput

0.618

High

954050

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

6

High-throughput

0.536

High

954054

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

9

Small-scale

0.515

High

954061

IF4H
Eukaryotic translation initiation factor 4H

1

20

High-throughput

0.481

High

586089

TFE2
Transcription factor E2-alpha

1

6

High-throughput

0.479

High

595155

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.479

High

915269

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

17

High-throughput

0.479

High

954044

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

954047

TFE3
Transcription factor E3

1

6

High-throughput

0.479

High

954051

FACD2
Fanconi anemia group D2 protein homolog

1

9

High-throughput

0.479

High

954055

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.479

High

954058

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

915507

HMGA2
High mobility group protein HMGI-C

1

1

High-throughput

0.445

High

954057

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

5

Small-scale

0.445

High

954060

DUS14
Dual specificity protein phosphatase 14

1

1

High-throughput

0.439

High

398218

CFAD
Complement factor D

1

2

High-throughput

0.437

High

954045

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.437

High

954048

Q6GTZ3
Idb1 protein

1

1

Small-scale

0.437

High

954053

MT21E
Protein-lysine methyltransferase METTL21E

1

5

High-throughput

0.437

High

954059

XPO7
Exportin-7

1

17

High-throughput

0.407

High


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Last updated: 11Aug2025