HitPredict - High confidence protein-protein interactions

Protein: PTGIS
Prostacyclin synthase (EC 5.3.99.4) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Prostaglandin I2 synthase)

Gene: PTGIS
Organism: Homo sapiens
Interactions: 7
UniProt ID: Q16647

Gene Ontology (top 5):
GO:0001516 - prostaglandin biosynthetic process
GO:0004497 - monooxygenase activity
GO:0005506 - iron ion binding
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1041091	CAV1 Caveolin-1	1	0	Small-scale	0.537	High
422187	A4 Amyloid-beta precursor protein	1	2	High-throughput	0.501	High
654825	PGH1 Prostaglandin G/H synthase 1	1	2	Small-scale	0.501	High
770775	PGH2 Prostaglandin G/H synthase 2	1	2	Small-scale	0.501	High
474704	VIME Vimentin	1	1	High-throughput	0.470	High
1160830	SAAL1 Protein SAAL1	1	0	High-throughput	0.426	High
1160831	TM169 Transmembrane protein 169	1	0	High-throughput	0.232	Low

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Last updated: 11Aug2025