Protein: TM169
Transmembrane protein 169

Gene: TM169, TMEM169
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q96HH4

Gene Ontology (top 5):
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

467288

MDR1
ATP-dependent translocase ABCB1

2

1

High-throughput

0.601

High

1393209

AGRL3
Adhesion G protein-coupled receptor L3

2

1

High-throughput

0.601

High

665666

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

2

0

High-throughput

0.576

High

1041226

CAV1
Caveolin-1

2

0

High-throughput

0.576

High

1110814

PKD2
Polycystin-2

2

0

High-throughput

0.576

High

1254305

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.576

High

1324303

GHDC
GH3 domain-containing protein

2

0

High-throughput

0.576

High

1335150

LEMD2
LEM domain-containing protein 2

2

0

High-throughput

0.576

High

1357935

DCAKD
Dephospho-CoA kinase domain-containing protein

2

0

High-throughput

0.576

High

1393191

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

2

0

High-throughput

0.576

High

1393197

NDC1
Nucleoporin NDC1

2

0

High-throughput

0.576

High

1393210

S38AA
Solute carrier family 38 member 10

2

0

High-throughput

0.576

High

1393214

ST7
Suppressor of tumorigenicity 7 protein

2

0

High-throughput

0.576

High

1393213

RTN4
Reticulon-4

2

3

High-throughput

0.549

High

1393216

ZDH18
Palmitoyltransferase ZDHHC18

2

2

High-throughput

0.549

High

1393204

FZD8
Frizzled-8

1

3

High-throughput

0.536

High

1393221

S12A6
Solute carrier family 12 member 6

1

1

High-throughput

0.536

High

249058

NRP2
Neuropilin-2

1

0

High-throughput

0.513

High

790171

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

0

High-throughput

0.513

High

845105

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

1058589

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.513

High

1208055

CYTSB
Cytospin-B

1

0

High-throughput

0.513

High

1231455

ATLA3
Atlastin-3

1

0

High-throughput

0.513

High

1251738

CERS6
Ceramide synthase 6

1

0

High-throughput

0.513

High

1357363

NAT14
Probable N-acetyltransferase 14

1

0

High-throughput

0.513

High

1359482

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.513

High

1369293

EDA
Ectodysplasin-A

1

0

High-throughput

0.513

High

1393193

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.513

High

1393202

SEM6A
Semaphorin-6A

1

0

High-throughput

0.513

High

1393227

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.513

High

1393233

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

0

High-throughput

0.513

High

275550

RTN2
Reticulon-2

1

3

High-throughput

0.489

High

1023441

AT8B2
Phospholipid-transporting ATPase ID

1

1

High-throughput

0.489

High

1125870

FZD2
Frizzled-2

1

3

High-throughput

0.489

High

1237957

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

1

High-throughput

0.489

High

1393196

REEP2
Receptor expression-enhancing protein 2

1

1

High-throughput

0.489

High

1393212

FZD3
Frizzled-3

1

3

High-throughput

0.489

High

1393226

ZDHC9
Palmitoyltransferase ZDHHC9

1

2

High-throughput

0.489

High

190630

MRP4
ATP-binding cassette sub-family C member 4

1

1

High-throughput

0.445

High

1310837

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

1

High-throughput

0.445

High

1393230

AGRG1
Adhesion G-protein coupled receptor G1

1

1

High-throughput

0.445

High

506642

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.437

High

296929

DGAT1
Diacylglycerol O-acyltransferase 1

1

0

High-throughput

0.426

High

297249

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.426

High

690346

STOM
Stomatin

1

0

High-throughput

0.426

High

1063068

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.426

High

1195372

ANO6
Anoctamin-6

1

0

High-throughput

0.426

High

1364105

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.426

High

1393192

SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

1

0

High-throughput

0.426

High

1393199

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.426

High

1393203

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.426

High

1393211

AT131
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.426

High

1393218

RN19A
E3 ubiquitin-protein ligase RNF19A

1

0

High-throughput

0.426

High

1393223

KDIS
Kinase D-interacting substrate of 220 kDa

1

0

High-throughput

0.426

High

1393229

FADS3
Fatty acid desaturase 3

1

0

High-throughput

0.426

High

85391

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

247533

FZD6
Frizzled-6

1

3

High-throughput

0.407

High

270675

ATP9A
Probable phospholipid-transporting ATPase IIA

1

1

High-throughput

0.407

High

328975

RTN3
Reticulon-3

1

3

High-throughput

0.407

High

1163599

RTN1
Reticulon-1

1

3

High-throughput

0.407

High

1393206

REEP4
Receptor expression-enhancing protein 4

1

1

High-throughput

0.407

High

1393207

ZDHC6
Palmitoyltransferase ZDHHC6

1

3

High-throughput

0.407

High

1393222

ZDHC2
Palmitoyltransferase ZDHHC2

1

2

High-throughput

0.407

High

1393231

S12A7
Solute carrier family 12 member 7

1

1

High-throughput

0.407

High

168885

PLD2
Phospholipase D2

2

0

High-throughput

0.313

High

170281

AURKA
Aurora kinase A

2

0

High-throughput

0.313

High

1241158

LTMD1
LETM1 domain-containing protein 1

2

0

High-throughput

0.313

High

1280180

RABEK
Rab9 effector protein with kelch motifs

2

0

High-throughput

0.313

High

1291456

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.313

High

1327713

MACOI
Macoilin

2

0

High-throughput

0.313

High

1329511

FITM2
Acyl-coenzyme A diphosphatase FITM2

2

0

High-throughput

0.313

High

1393195

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

2

0

High-throughput

0.313

High

1393225

CIA30
Complex I intermediate-associated protein 30, mitochondrial

2

0

High-throughput

0.313

High

171556

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.279

Low

253883

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

397808

ATP8
ATP synthase F(0) complex subunit 8

1

0

High-throughput

0.279

Low

560992

GP1BB
Platelet glycoprotein Ib beta chain

1

0

High-throughput

0.279

Low

611287

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.279

Low

732671

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.279

Low

1022934

EFNB1
Ephrin-B1

1

0

High-throughput

0.279

Low

1211948

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.279

Low

1237884

MYORG
Myogenesis-regulating glycosidase

1

0

High-throughput

0.279

Low

1238890

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.279

Low

1240395

M18BP
Mis18-binding protein 1

1

0

High-throughput

0.279

Low

1242991

CV039
Synaptic plasticity regulator PANTS

1

0

High-throughput

0.279

Low

1278072

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.279

Low

1358437

LMBR1
Limb region 1 protein homolog

1

0

High-throughput

0.279

Low

1392778

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

1393190

CAR19
Caspase recruitment domain-containing protein 19

1

0

High-throughput

0.279

Low

1393198

FICD
Protein adenylyltransferase FICD

1

0

High-throughput

0.279

Low

1393205

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

1393219

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.279

Low

1393220

SELN
Selenoprotein N

1

0

High-throughput

0.279

Low

1393224

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.279

Low

1393228

TBL2
Transducin beta-like protein 2

1

0

High-throughput

0.279

Low

1393232

ATP23
Mitochondrial inner membrane protease ATP23 homolog

1

0

High-throughput

0.279

Low

1270944

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.261

Low

75548

B3KSP9
Alanyl-tRNA editing protein Aarsd1

1

0

High-throughput

0.232

Low

403207

APOB
Apolipoprotein B-100

1

0

High-throughput

0.232

Low

770811

HRH1
Histamine H1 receptor

1

0

High-throughput

0.232

Low

1013206

ATL3
ADAMTS-like protein 3

1

0

High-throughput

0.232

Low

1126285

GP176
G-protein coupled receptor 176

1

0

High-throughput

0.232

Low

1159171

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.232

Low

1160831

PTGIS
Prostacyclin synthase

1

0

High-throughput

0.232

Low

1245263

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

0

High-throughput

0.232

Low

1248371

UQCC3
Ubiquinol-cytochrome-c reductase complex assembly factor 3

1

0

High-throughput

0.232

Low

1270280

BT2A1
Butyrophilin subfamily 2 member A1

1

0

High-throughput

0.232

Low

1322829

ORML3
ORM1-like protein 3

1

0

High-throughput

0.232

Low

1339278

RAI3
Retinoic acid-induced protein 3

1

0

High-throughput

0.232

Low

1381914

C102A
Coiled-coil domain-containing protein 102A

1

0

High-throughput

0.232

Low

1393194

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.232

Low

1393200

STRA6
Receptor for retinol uptake STRA6

1

0

High-throughput

0.232

Low

1393201

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.232

Low

1393208

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.232

Low

1393215

TEN2
Teneurin-2

1

0

High-throughput

0.232

Low

1393217

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025