Protein: PGH1
Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1)

Gene: PGH1, PTGS1
Organism: Homo sapiens
Interactions: 16
UniProt ID: P23219

Gene Ontology (top 5):
GO:0001516 - prostaglandin biosynthetic process
GO:0001750 - photoreceptor outer segment
GO:0004601 - peroxidase activity
GO:0004666 - prostaglandin-endoperoxide synthase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

654818

PGH2
Prostaglandin G/H synthase 2

1

2

Small-scale

0.618

High

654828

RFFL
E3 ubiquitin-protein ligase rififylin

1

1

High-throughput

0.515

High

547968

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

654825

PTGIS
Prostacyclin synthase

1

2

Small-scale

0.501

High

654821

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

1

0

High-throughput

0.493

High

654822

CAV1
Caveolin-1

1

2

Small-scale

0.479

High

654823

EEA1
Early endosome antigen 1

1

2

High-throughput

0.479

High

654826

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

654831

FBX6
F-box only protein 6

1

3

High-throughput

0.479

High

654824

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

217838

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

654820

CAV2
Caveolin-2

1

2

Small-scale

0.437

High

654819

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.268

Low

654830

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

0

High-throughput

0.268

Low

654827

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

654829

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025