Protein: DPH6
Diphthine--ammonia ligase (EC 6.3.1.14) (Diphthamide synthase) (Diphthamide synthetase)

Gene: DPH6
Organism: Saccharomyces cerevisiae S288C
Interactions: 15
UniProt ID: Q12429

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0017178 - diphthine-ammonia ligase activity
GO:0017183 - protein histidyl modification to diphthamide

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

867602

ALDH2
Aldehyde dehydrogenase [NAD(P)+] 1

1

0

High-throughput

0.493

High

865295

LSM8
LSM2-LSM8 complex subunit LSM8

1

0

High-throughput

0.486

High

435448

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

865343

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

922663

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

925156

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

1059438

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

525626

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

782662

PXL1
Paxillin-like protein 1

1

0

High-throughput

0.426

High

820183

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

844459

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

455326

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

708596

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

734237

EF2
Elongation factor 2

1

0

Small-scale

0.249

Low

1044855

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025