Protein: MTNB
Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109)

Gene: MTNB, MDE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P47095

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0019509 - L-methionine salvage from methylthioadenosine
GO:0046570 - methylthioribulose 1-phosphate dehydratase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

865308

MTNB
Methylthioribulose-1-phosphate dehydratase

2

7

High-throughput

0.778

High

509621

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

656328

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

1

High-throughput

0.479

High

707520

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

708761

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

752024

PGM1
Phosphoglucomutase 1

1

1

High-throughput

0.479

High

815824

BEM2
GTPase-activating protein BEM2/IPL2

1

1

High-throughput

0.479

High

416891

CDC25
Cell division control protein 25

1

0

High-throughput

0.458

High

471419

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.458

High

514715

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

604964

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

618604

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.458

High

668317

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

673058

SED4
Putative guanine nucleotide-exchange factor SED4

1

0

High-throughput

0.458

High

678243

BUD23
18S rRNA

1

0

High-throughput

0.458

High

678700

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.458

High

736675

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.458

High

757930

YEL1
Guanine-nucleotide exchange factor YEL1

1

0

High-throughput

0.458

High

758065

ASH1
Transcriptional regulatory protein ASH1

1

0

High-throughput

0.458

High

776481

MPE1
Protein MPE1

1

0

High-throughput

0.458

High

800940

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.458

High

801178

SIC1
Protein SIC1

1

0

High-throughput

0.458

High

804996

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.458

High

806108

SOL3
6-phosphogluconolactonase 3

1

0

High-throughput

0.458

High

816590

GEA2
ARF guanine-nucleotide exchange factor 2

1

0

High-throughput

0.458

High

820496

PCL7
PHO85 cyclin-7

1

0

High-throughput

0.458

High

865309

YJ66
Uncharacterized oxidoreductase YJR096W

1

0

High-throughput

0.458

High

865310

PXP2
Peroxisomal protein 2

1

0

High-throughput

0.458

High

865312

CTH2
mRNA decay factor CTH2

1

0

High-throughput

0.458

High

865314

NIT3
Omega-amidase NIT3

1

0

High-throughput

0.458

High

865316

PHO23
Transcriptional regulatory protein PHO23

1

0

High-throughput

0.458

High

865317

SHE4
SWI5-dependent HO expression protein 4

1

0

High-throughput

0.458

High

865318

NBP35
Cytosolic Fe-S cluster assembly factor NBP35

1

0

High-throughput

0.458

High

865323

OSH6
Oxysterol-binding protein homolog 6

1

0

High-throughput

0.458

High

865324

TRM44
tRNA

1

0

High-throughput

0.458

High

865325

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.458

High

865327

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.458

High

865328

PPN1
Endopolyphosphatase

1

0

High-throughput

0.458

High

865329

TR120
Trafficking protein particle complex II-specific subunit 120

1

0

High-throughput

0.458

High

865330

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

865331

CYK2
Cytokinesis protein 2

1

0

High-throughput

0.458

High

865333

FUS2
Nuclear fusion protein FUS2

1

0

High-throughput

0.458

High

865335

BCP1
Protein BCP1

1

0

High-throughput

0.458

High

865339

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.458

High

865343

DPH6
Diphthine--ammonia ligase

1

0

High-throughput

0.458

High

746448

SSO1
Protein SSO1

1

3

High-throughput

0.437

High

758114

CASP
Protein CASP

1

2

High-throughput

0.437

High

781346

PRY2
Protein PRY2

1

2

High-throughput

0.437

High

790581

VRP1
Verprolin

1

1

High-throughput

0.437

High

865322

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.437

High

865332

SGPL
Sphingosine-1-phosphate lyase

1

1

High-throughput

0.437

High

865342

ORT1
Mitochondrial ornithine transporter 1

1

1

High-throughput

0.437

High

819147

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

368176

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.249

Low

402230

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

0

High-throughput

0.249

Low

677938

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.249

Low

694476

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

702259

YJU2
Splicing factor YJU2

1

0

High-throughput

0.249

Low

744206

RAD24
Checkpoint protein RAD24

1

0

High-throughput

0.249

Low

744794

LAA2
Clathrin adapter accessory protein LAA2

1

0

High-throughput

0.249

Low

751975

LHP1
La protein homolog

1

0

High-throughput

0.249

Low

781082

TCD2
tRNA threonylcarbamoyladenosine dehydratase 2

1

0

High-throughput

0.249

Low

781683

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.249

Low

782139

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.249

Low

784328

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

797493

EXO5
Exonuclease V, mitochondrial

1

0

High-throughput

0.249

Low

804698

HTD2
Hydroxyacyl-thioester dehydratase type 2, mitochondrial

1

0

High-throughput

0.249

Low

807240

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.249

Low

808285

RRP8
25S rRNA

1

0

High-throughput

0.249

Low

817801

NU157
Nucleoporin NUP157

1

0

High-throughput

0.249

Low

830134

NOP2
25S rRNA

1

0

High-throughput

0.249

Low

865311

TDA4
Topoisomerase I damage affected protein 4

1

0

High-throughput

0.249

Low

865313

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.249

Low

865315

ATP22
Mitochondrial translation factor ATP22

1

0

High-throughput

0.249

Low

865319

INO80
Chromatin-remodeling ATPase INO80

1

0

High-throughput

0.249

Low

865320

FLC3
Putative flavin carrier protein 3

1

0

High-throughput

0.249

Low

865321

MKC7
Aspartic proteinase MKC7

1

0

High-throughput

0.249

Low

865326

TCB3
Tricalbin-3

1

0

High-throughput

0.249

Low

865334

SEI1
Seipin

1

0

High-throughput

0.249

Low

865336

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.249

Low

865337

MDM38
Mitochondrial distribution and morphology protein 38

1

0

High-throughput

0.249

Low

865338

ENV9
Probable oxidoreductase ENV9

1

0

High-throughput

0.249

Low

865340

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.249

Low

865341

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

865344

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.249

Low

865345

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025