HitPredict - High confidence protein-protein interactions

Protein: HME2
Homeobox protein engrailed-2 (Homeobox protein en-2) (Hu-En-2)

Gene: HME2, EN2
Organism: Homo sapiens
Interactions: 5
UniProt ID: P19622

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
624539	TLE1 Transducin-like enhancer protein 1	1	20	High-throughput	0.536	High
624540	NDOR1 NADPH-dependent diflavin oxidoreductase 1	1	0	High-throughput	0.513	High
445493	IF4E Eukaryotic translation initiation factor 4E	1	3	Small-scale	0.501	High
624541	FOXA2 Hepatocyte nuclear factor 3-beta	1	20	Small-scale	0.501	High
624538	EWS RNA-binding protein EWS	1	2	High-throughput	0.479	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025