Protein: FOXA2
Hepatocyte nuclear factor 3-beta (HNF-3-beta) (HNF-3B) (Forkhead box protein A2) (Transcription factor 3B) (TCF-3B)

Gene: FOXA2
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q9Y261

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733759

FOXN2
Forkhead box protein N2

1

20

High-throughput

0.691

High

634895

HXA5
Homeobox protein Hox-A5

2

20

Small-scale

0.602

High

733278

OTX2
Homeobox protein OTX2

2

13

Small-scale

0.602

High

1047886

TLE1
Transducin-like enhancer protein 1

2

20

Small-scale

0.601

High

1490505

FOXA2
Hepatocyte nuclear factor 3-beta

1

18

High-throughput

0.575

High

1458270

HNF6
Hepatocyte nuclear factor 6

1

14

Small-scale

0.561

High

771620

HXD13
Homeobox protein Hox-D13

1

20

High-throughput

0.536

High

937377

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

12

High-throughput

0.536

High

1369126

HXB13
Homeobox protein Hox-B13

1

20

High-throughput

0.536

High

1401294

NACC1
Nucleus accumbens-associated protein 1

1

15

High-throughput

0.536

High

1449311

SALL1
Sal-like protein 1

1

8

High-throughput

0.536

High

1460224

DACH1
Dachshund homolog 1

1

4

High-throughput

0.536

High

1462603

SATB2
DNA-binding protein SATB2

1

20

High-throughput

0.536

High

772638

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.513

High

624541

HME2
Homeobox protein engrailed-2

1

20

Small-scale

0.501

High

877577

LHX1
LIM/homeobox protein Lhx1

1

4

Small-scale

0.501

High

942481

GSC
Homeobox protein goosecoid

1

20

Small-scale

0.501

High

570637

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.493

High

896938

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

1279807

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1153797

NCOA1
Nuclear receptor coactivator 1

1

6

Small-scale

0.481

High

1212132

OTUD3
OTU domain-containing protein 3

1

0

Small-scale

0.480

High

474385

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

851825

NKX21
Homeobox protein Nkx-2.1

1

20

Small-scale

0.479

High

1005254

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1339236

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

1459350

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

369784

A2MG
Alpha-2-macroglobulin

1

4

High-throughput

0.470

High

622302

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

2

High-throughput

0.470

High

1295257

PRGC2
Peroxisome proliferator-activated receptor gamma coactivator 1-beta

1

0

Small-scale

0.458

High

377782

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025