HitPredict
Protein: NKX21
Homeobox protein Nkx-2.1 (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP)

Gene: NKX21, Nkx2-1
Organism: Mus musculus
Interactions: 13
UniProt ID: P50220

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

484838

 HXA9
Homeobox protein Hox-A9

1

20

High-throughput

 0.698

High

893666

 EMX2
Homeobox protein EMX2

1

19

High-throughput

 0.698

High

893669

 HXC12
Homeobox protein Hox-C12

1

20

High-throughput

 0.698

High

893670

 VSX1
Visual system homeobox 1

1

19

High-throughput

 0.698

High

893672

 MIXL1
Homeobox protein MIXL1

1

19

High-throughput

 0.698

High

725352

 GSX2
GS homeobox 2

1

19

High-throughput

 0.621

High

845944

 NR2F6
Nuclear receptor subfamily 2 group F member 6

1

11

High-throughput

 0.541

High

893665

 PAX8
Paired box protein Pax-8

1

15

High-throughput

 0.541

High

893673

 HNF4G
Hepatocyte nuclear factor 4-gamma

1

12

High-throughput

 0.541

High

893668

 GATA6
Transcription factor GATA-6

1

16

High-throughput

 0.481

High

893667

 SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

 0.479

High

893671

 SPDEF
SAM pointed domain-containing Ets transcription factor

1

19

Small-scale

 0.479

High

893664

 HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

 0.426

High

Service provided by Combinatics, Japan

Last updated: 11Aug2025