Protein: ISC1
Inositol phosphosphingolipids phospholipase C (IPS phospholipase C) (IPS-PLC) (EC 3.1.4.-) (Neutral sphingomyelinase) (N-SMase) (nSMase)

Gene: ISC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 16
UniProt ID: P40015

Gene Ontology (top 5):
GO:0004767 - sphingomyelin phosphodiesterase activity
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817055

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

1

Small-scale

0.501

High

817056

ORM2
Protein ORM2

1

0

High-throughput

0.486

High

782010

PET10
Protein PET10

1

0

High-throughput

0.460

High

579459

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

817053

DNM1
Dynamin-related protein DNM1

1

0

Small-scale

0.458

High

817057

FLC1
Flavin carrier protein 1

1

0

High-throughput

0.458

High

678558

ATG15
Putative lipase ATG15

1

0

High-throughput

0.438

High

817052

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.438

High

817054

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

545003

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

741652

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

817050

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

554698

YPK1
Serine/threonine-protein kinase YPK1

1

0

Small-scale

0.249

Low

817051

RTS2
Zinc finger protein RTS2

1

0

High-throughput

0.249

Low

524063

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.232

Low

670754

SIS1
Protein SIS1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025