Protein: ORM2
Protein ORM2

Gene: ORM2
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: Q06144

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006672 - ceramide metabolic process
GO:0006986 - response to unfolded protein
GO:0017059 - serine palmitoyltransferase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

668465

SPTC1
Serine palmitoyltransferase 1

9

8

Small-scale

0.973

High

829998

LCB2
Serine palmitoyltransferase 2

6

8

Small-scale

0.943

High

1053898

ORM2
Protein ORM2

4

2

Small-scale

0.692

High

735868

SAC1
Phosphatidylinositol-3-phosphatase SAC1

4

1

Small-scale

0.683

High

918362

ORM1
Protein ORM1

3

2

Small-scale

0.653

High

1053905

UBX3
UBX domain-containing protein 3

3

0

Small-scale

0.613

High

1053908

TSC3
Serine palmitoyltransferase-regulating protein TSC3

2

1

Small-scale

0.611

High

554735

YPK1
Serine/threonine-protein kinase YPK1

2

1

Small-scale

0.602

High

797058

PHO88
SRP-independent targeting protein 3

2

0

High-throughput

0.588

High

754663

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

2

0

High-throughput

0.587

High

1053899

GPI13
GPI ethanolamine phosphate transferase 3

2

0

High-throughput

0.587

High

1050270

DFG5
Mannan endo-1,6-alpha-mannosidase DFG5

2

0

High-throughput

0.582

High

1053900

DSC2
DSC E3 ubiquitin ligase complex subunit 2

2

0

Small-scale

0.559

High

1053903

DSC3
DSC E3 ubiquitin ligase complex subunit 3

2

0

Small-scale

0.559

High

673313

ADP1
Probable ATP-dependent permease

1

2

High-throughput

0.541

High

798671

SSH1
Sec sixty-one protein homolog

1

1

High-throughput

0.541

High

808698

SUR2
Sphingolipid C4-hydroxylase SUR2

1

2

High-throughput

0.541

High

916781

ERG25
C-4 methylsterol oxidase ERG25

1

2

High-throughput

0.541

High

932634

TMEDA
Endoplasmic reticulum vesicle protein 25

1

1

High-throughput

0.541

High

1050964

ERP1
Protein ERP1

1

1

High-throughput

0.541

High

1053907

ERP4
Protein ERP4

1

1

High-throughput

0.541

High

546342

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.521

High

751122

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

2

High-throughput

0.518

High

903537

PDR10
ATP-dependent permease PDR10

1

2

High-throughput

0.518

High

1053901

YO075
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C

1

2

High-throughput

0.518

High

528642

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.518

High

812901

SOP4
Protein SOP4

1

0

High-throughput

0.518

High

826154

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.518

High

863343

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.518

High

918149

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

1

0

High-throughput

0.518

High

1038524

SHR3
Secretory component protein SHR3

1

0

High-throughput

0.518

High

1038804

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.518

High

1043262

SCS7
Ceramide very long chain fatty acid hydroxylase SCS7

1

0

High-throughput

0.518

High

1050115

SPC2
Signal peptidase complex subunit 2

1

0

High-throughput

0.518

High

656623

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

800921

NCB5R
NADH-cytochrome b5 reductase 1

1

1

High-throughput

0.494

High

817056

ISC1
Inositol phosphosphingolipids phospholipase C

1

0

High-throughput

0.486

High

1042492

PEX29
Peroxisomal membrane protein PEX29

1

0

High-throughput

0.486

High

703851

LAC1
Ceramide synthase LAC1

1

2

Small-scale

0.479

High

1053909

ENV10
SRP-independent targeting protein 2

1

2

High-throughput

0.479

High

441258

KAPA
cAMP-dependent protein kinase type 1

1

3

High-throughput

0.457

High

646161

NPR1
Nitrogen permease reactivator protein

1

2

Small-scale

0.457

High

748900

SWE1
Mitosis inhibitor protein kinase SWE1

1

5

High-throughput

0.457

High

850969

TOS3
Serine/threonine-protein kinase TOS3

1

1

High-throughput

0.457

High

865547

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

3

High-throughput

0.457

High

735362

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

2

High-throughput

0.457

High

748549

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.457

High

793253

BAP2
Leu/Val/Ile amino-acid permease

1

2

High-throughput

0.457

High

1047165

ERV41
ER-derived vesicles protein ERV41

1

3

High-throughput

0.457

High

802019

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

0

High-throughput

0.438

High

1035104

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

1043338

GOT1
Protein transport protein GOT1

1

0

High-throughput

0.438

High

394921

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.437

High

525202

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.437

High

527720

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.437

High

819843

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.407

High

1053904

CCW12
Covalently-linked cell wall protein 12

3

0

High-throughput

0.340

High

781029

TUL1
Transmembrane E3 ubiquitin-protein ligase 1

3

0

Small-scale

0.334

High

1053906

SMT3
Ubiquitin-like protein SMT3

2

0

High-throughput

0.313

High

738564

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.282

High

924161

PGA14
Hydrophilin YNL190W

1

0

High-throughput

0.282

High

1053902

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

1

0

High-throughput

0.282

High

812934

UIP3
ULP1-interacting protein 3

1

0

High-throughput

0.265

Low

917173

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

359357

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.249

Low

365194

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

368061

ENO2
Enolase 2

1

0

High-throughput

0.249

Low

444627

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.249

Low

592511

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.249

Low

708227

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

737949

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.249

Low

804471

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.249

Low

812120

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.249

Low

865646

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025