Protein: THI6
Thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (THZ kinase)]

Gene: THI6
Organism: Saccharomyces cerevisiae S288C
Interactions: 13
UniProt ID: P41835

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004417 - hydroxyethylthiazole kinase activity
GO:0004789 - thiamine-phosphate diphosphorylase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

836383

THI6
Thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase

1

3

High-throughput

0.656

High

836384

ACAC
Acetyl-CoA carboxylase

1

0

Small-scale

0.460

High

679797

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

781942

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

836386

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

836385

IMA1
Importin subunit alpha

1

1

High-throughput

0.457

High

545244

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

819021

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

526948

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

670836

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

816258

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

707380

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025