HitPredict
Protein: PGH2
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (Glucocorticoid-regulated inflammatory cyclooxygenase) (Gripghs) (Macrophage activation-associated marker protein P71/73) (PES-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2) (TIS10 protein)

Gene: PGH2, Ptgs2
Organism: Mus musculus
Interactions: 13
UniProt ID: Q05769

Gene Ontology (top 5):
GO:0001516 - prostaglandin biosynthetic process
GO:0004601 - peroxidase activity
GO:0004666 - prostaglandin-endoperoxide synthase activity
GO:0005637 - nuclear inner membrane
GO:0005640 - nuclear outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

1052198

 PGH2
Prostaglandin G/H synthase 2

2

2

Small-scale

 0.755

High

583145

 IRF1
Interferon regulatory factor 1

2

1

Small-scale

 0.612

High

663329

 IRF2
Interferon regulatory factor 2

2

1

Small-scale

 0.612

High

1052203

 NOS1
Nitric oxide synthase 1

1

1

Small-scale

 0.515

High

1039010

 NUCB1
Nucleobindin-1

1

2

Small-scale

 0.481

High

713202

 NOS2
Nitric oxide synthase, inducible

1

1

Small-scale

 0.479

High

1000294

 ELAV1
ELAV-like protein 1

1

1

Small-scale

 0.479

High

1052200

 UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

High-throughput

 0.479

High

1052199

 HIF1A
Hypoxia-inducible factor 1-alpha

1

0

Small-scale

 0.458

High

1052202

 SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

Small-scale

 0.458

High

1052201

 BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

2

High-throughput

 0.437

High

591042

 KPCE
Protein kinase C epsilon type

1

0

Small-scale

 0.426

High

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Last updated: 11Aug2025